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儿童白内障的管理与治疗结果:多伦多的经验

Management and outcomes of cataract in children: the Toronto experience.

作者信息

Lim Zena, Rubab Shehla, Chan Yiong H, Levin Alex V

机构信息

Singapore National Eye Centre, Singapore.

出版信息

J AAPOS. 2012 Jun;16(3):249-54. doi: 10.1016/j.jaapos.2011.12.158.

Abstract

PURPOSE

To review the management and outcomes of pediatric patients with cataract who were managed by one of two surgeons at a single institution.

METHODS

An observational series of consecutive cases identified from the hospital's outpatient billing records and surgical data program were used. Visual acuity was measured with the Snellen or Allen charts. Glaucoma was defined as IOP >20 mm Hg with clinical signs of glaucoma or visual field loss. Procedures for aphakic/pseudophakic glaucoma were excluded from analysis of additional surgeries performed subsequent to cataract extraction.

RESULTS

The search identified 778 patients (1,122 eyes) diagnosed with cataract over 10 years. Of these, 74% of eyes were treated surgically. Those patients with total, nuclear, and lamellar cataracts were significantly more likely than the overall population to undergo surgery. Additional surgeries were required in 12% of surgically treated eyes, with pseudophakic eyes representing more than one-half. Aphakic and pseudophakic glaucoma prevalence were 12% and 1%, respectively. Cataract morphology was not found to be a predisposing factor in the development of glaucoma. Visual outcomes were significantly better for posterior subcapsular (P = 0.0001), nuclear (P = 0.025), lamellar (P = 0.03), and traumatic cataracts (P = 0.005) than for other morphological types at all ages. Visual acuity was 20/30 or better in 63% of children with unilateral pseudophakia, 45% of children with unilateral aphakia, and approximately 75% of children with bilateral aphakia and pseudophakia.

CONCLUSIONS

Patients with total, nuclear, and lamellar cataracts were more likely to undergo surgery. Approximately 10% of patients required additional surgeries. No cataract morphology predisposed patients to developing glaucoma. Good visual outcomes were attained in bilaterally pseudophakic/aphakic and unilaterally pseudophakic children.

摘要

目的

回顾在单一机构由两位外科医生之一管理的小儿白内障患者的治疗及预后情况。

方法

采用从医院门诊计费记录和手术数据程序中识别出的连续病例的观察性系列研究。使用斯内伦或艾伦视力表测量视力。青光眼定义为眼压>20 mmHg且伴有青光眼临床体征或视野缺损。白内障摘除术后进行的其他手术分析中排除无晶状体/人工晶状体性青光眼的手术。

结果

该研究共纳入10年间诊断为白内障的778例患者(1122只眼)。其中,74%的患眼接受了手术治疗。患有全白内障、核性白内障和板层白内障的患者比总体人群更有可能接受手术。12%的手术治疗患眼需要额外手术,其中人工晶状体眼占一半以上。无晶状体性和人工晶状体性青光眼的患病率分别为12%和1%。未发现白内障形态是青光眼发生的易感因素。在所有年龄段,后囊下白内障(P = 0.0001)、核性白内障(P = 0.025)、板层白内障(P = 0.03)和外伤性白内障(P = 0.005)的视力预后明显优于其他形态类型。单侧人工晶状体眼的儿童中63%视力为20/30或更好,单侧无晶状体眼的儿童中45%视力为20/30或更好,双侧无晶状体眼和人工晶状体眼的儿童中约75%视力为20/30或更好。

结论

患有全白内障、核性白内障和板层白内障的患者更有可能接受手术。约10%的患者需要额外手术。没有白内障形态使患者易患青光眼。双侧人工晶状体/无晶状体眼和单侧人工晶状体眼的儿童获得了良好的视力预后。

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