Department of Neurology, Juntendo Koshigaya Hospital, 560 Fukuroyama, Koshigaya, Saitama, Japan.
Parkinsonism Relat Disord. 2012 Sep;18(8):986-9. doi: 10.1016/j.parkreldis.2012.05.006. Epub 2012 Jun 7.
We report on 8 patients with Parkinson's disease (PD) who experienced suddenly episodes of speech unrelated to the topic of conversation or wrote sentences unrelated to the context. During these episodes and later, unless pointed out, patients were unaware of the behavior. We called this phenomenon Unrelated Communication Interlude (UCI). All patients were male; half of them with impulse control disorders (punding, hypersexuality, or pathological gambling). Four patients reported sleepiness when the episodes of UCI occurred. There were no significant differences in age at examination, age of onset of PD, and neuropsychological tests score (Mini-Mental State Examination, Frontal Assessment Battery, and Beck Depression Inventory) between patients with UCI and those without. To our knowledge, this is the first reported phenomena of such abnormal behavior in Parkinson's disease. UCI was considered as automatic behavior similar to that seen in narcolepsy and excessive daytime sleepiness. UCI might be occurring in relation to excessive daytime sleepiness in PD.
我们报告了 8 例帕金森病（PD）患者，他们突然出现与谈话主题无关的言语片段，或写出与上下文无关的句子。在这些发作期间和之后，除非被指出，否则患者没有意识到这种行为。我们将这种现象称为无关沟通插曲（UCI）。所有患者均为男性，其中一半伴有冲动控制障碍（冲动性购物、性欲亢进或病理性赌博）。4 例患者报告说，当 UCI 发作时会感到困倦。发作 UCI 的患者与无 UCI 的患者之间，在检查时的年龄、PD 发病年龄和神经心理学测试评分（简易精神状态检查、额叶评估量表和贝克抑郁量表）方面没有显著差异。据我们所知，这是首次在帕金森病中报告这种异常行为的现象。UCI 被认为是类似于发作性睡病和日间过度嗜睡中所见的自动行为。在 PD 中，UCI 可能与日间过度嗜睡有关。
