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合并症-多药治疗评分:急诊创伤分诊的新辅助手段。

Comorbidity-polypharmacy score: a novel adjunct in post-emergency department trauma triage.

机构信息

Division of Critical Care, Trauma, and Burn, Department of Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA.

出版信息

J Surg Res. 2013 May 1;181(1):16-9. doi: 10.1016/j.jss.2012.05.042. Epub 2012 May 31.

Abstract

OBJECTIVE

Post-emergency department triage of older trauma patients continues to be challenging, as morbidity and mortality for any given level of injury severity tend to increase with age. The comorbidity-polypharmacy score (CPS) combines the number of pre-injury medications with the number of comorbidities to estimate the severity of comorbid conditions. This retrospective study examines the relationship between CPS and triage accuracy for older (≥45y) patients admitted for traumatic injury.

METHODS

Patients aged 45y and older presenting to level 1 trauma center from 2005 to 2008 were included. Basic data included patient demographics, injury severity score, morbidity and mortality, and functional outcome measures. CPS was calculated by adding total numbers of comorbid conditions and pre-injury medications. Patients were divided into three triage groups: undertriage (UT), appropriate triage (AT), and overtriage (OT). UT criteria included initial admission to the floor or step-down unit followed by an unplanned transfer to intensive care unit (ICU) within 24h of admission. OT was defined as initial ICU admission for <1d without stated need for ICU level of care (i.e., lack of evidence for tracheal intubation or mechanical ventilation, injury-related hemorrhage, or other traditional ICU indications, such as intracranial bleeding). All other patients were presumed to be correctly triaged. The three triage groups were then analyzed looking for contributors to mistriage.

RESULTS

Charts for 711 patients were evaluated (mean age, 63.5y; 55.7% male; mean ISS, 9.02). Of those, 11 (1.55%) met criteria for UT and 14 (1.97%) for OT. The remaining 686 patients had no evidence of mistriage. The three groups were similar in terms of injury severity and GCS. The groups were significantly different with respect to CPS, with UT CPSs (14.9±6.80) being nearly three times higher than OT CPSs (5.14±3.48). There were more similarities between AT and OT groups, with the UT group being characterized by greater number of complications and lower functional outcomes at discharge (all, P<0.05). The UT group had significantly higher mortality (27%) than the AT and OT groups (6% and 0%, respectively).

CONCLUSIONS

In the era of medication reconciliation, CPS is easy to obtain and calculate in patients who are not critically injured. This study suggests that CPS may be a promising adjunct in identifying older trauma patients who are more likely to be undertriaged. The significance of our findings is especially important when considering that injury severity in the UT group was similar to that in the other groups. Further evaluation of CPS as a triage tool in acute trauma is warranted.

摘要

目的

对急诊科分诊的老年创伤患者仍然具有挑战性,因为任何特定严重程度的损伤,其发病率和死亡率都随着年龄的增长而增加。合并症-多药治疗评分(CPS)将受伤前的药物数量与合并症数量相结合,以估计合并症的严重程度。本回顾性研究检查了 CPS 与因创伤而入院的老年(≥45 岁)患者分诊准确性之间的关系。

方法

纳入了 2005 年至 2008 年期间在一级创伤中心就诊的年龄在 45 岁及以上的患者。基本数据包括患者人口统计学资料、损伤严重程度评分、发病率和死亡率以及功能预后指标。通过添加合并症和受伤前药物的总数来计算 CPS。患者被分为三组:分诊不足(UT)、适当分诊(AT)和分诊过度(OT)。UT 标准包括初始入院至病房或降级单位,然后在入院后 24 小时内计划转入重症监护病房(ICU)。OT 定义为最初 ICU 入住时间<1 天,无 ICU 级护理需求(即无气管插管或机械通气、损伤相关出血或其他传统 ICU 指征,如颅内出血)。所有其他患者被假定为正确分诊。然后分析这三组患者,寻找分诊错误的原因。

结果

评估了 711 份图表(平均年龄 63.5 岁;55.7%为男性;平均 ISS 9.02)。其中,11 例(1.55%)符合 UT 标准,14 例(1.97%)符合 OT 标准。其余 686 例患者没有分诊错误的证据。这三组在损伤严重程度和 GCS 方面相似。三组在 CPS 方面存在显著差异,UT 组 CPS(14.9±6.80)几乎是 OT 组 CPS(5.14±3.48)的三倍。AT 和 OT 组之间有更多的相似之处,UT 组的并发症和出院时的功能结果较低(均 P<0.05)。UT 组的死亡率(27%)明显高于 AT 和 OT 组(分别为 6%和 0%)。

结论

在药物调整时代,CPS 很容易在未受伤的患者中获得和计算。本研究表明,CPS 可能是一种很有前途的辅助手段,可用于识别更容易分诊不足的老年创伤患者。我们的研究结果意义重大,尤其是在考虑到 UT 组的损伤严重程度与其他组相似的情况下。需要进一步评估 CPS 作为急性创伤的分诊工具。

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