纳米医学全景：研究中及已批准的纳米医学产品状况。
The big picture on nanomedicine: the state of investigational and approved nanomedicine products.
机构信息
Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
出版信息
Nanomedicine. 2013 Jan;9(1):1-14. doi: 10.1016/j.nano.2012.05.013. Epub 2012 Jun 6.
UNLABELLED
Developments in nanomedicine are expected to provide solutions to many of modern medicine's unsolved problems, so it is no surprise that the literature contains many articles discussing the subject. However, existing reviews tend to focus on specific sectors of nanomedicine or to take a very forward-looking stance and fail to provide a complete perspective on the current landscape. This article provides a more comprehensive and contemporary inventory of nanomedicine products. A keyword search of literature, clinical trial registries, and the Web yielded 247 nanomedicine products that are approved or in various stages of clinical study. Specific information on each was gathered, so the overall field could be described based on various dimensions, including FDA classification, approval status, nanoscale size, treated condition, nanostructure, and others. In addition to documenting the many nanomedicine products already in use in humans, this study identifies several interesting trends forecasting the future of nanomedicine.
FROM THE CLINICAL EDITOR
In this one of a kind review, the state of nanomedicine commercialization is discussed, concentrating only on nanomedicine-based developments and products that are either in clinical trials or have already been approved for use.
未加标签
纳米医学的发展有望为现代医学的许多未解决的问题提供解决方案，因此，文献中包含许多讨论该主题的文章也就不足为奇了。然而，现有的评论往往侧重于纳米医学的特定领域，或者采取非常前瞻性的立场，未能提供对当前格局的全面视角。本文提供了更全面和现代的纳米医学产品清单。通过对文献、临床试验注册处和网络进行关键字搜索，共发现 247 种已批准或处于临床研究各个阶段的纳米医学产品。对每个产品都收集了具体信息，因此可以根据各种维度（包括 FDA 分类、批准状态、纳米级尺寸、治疗状况、纳米结构等）对整个领域进行描述。除了记录已经在人类中使用的许多纳米医学产品外，本研究还确定了一些预测纳米医学未来发展的有趣趋势。
临床编辑按
在这篇独一无二的评论中，讨论了纳米医学商业化的现状，仅关注处于临床试验或已获准使用的基于纳米医学的开发和产品。
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