Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Phys Med Biol. 2012 Jul 7;57(13):4211-21. doi: 10.1088/0031-9155/57/13/4211. Epub 2012 Jun 8.
The purpose of this study was to investigate the possibility of estimating pediatric thyroid doses from CT using surface neck doses. Optically stimulated luminescence dosimeters were used to measure the neck surface dose of 25 children ranging in ages between one and three years old. The neck circumference for each child was measured. The relationship between obtained surface doses and thyroid dose was studied using acrylic phantoms of various sizes and with holes of different depths. The ratios of hole-to-surface doses were used to convert patients' surface dose to thyroid dose. ImPACT software was utilized to calculate thyroid dose after applying the appropriate age correction factors. A paired t-test was performed to compare thyroid doses from our approach and ImPACT. The ratio of thyroid to surface dose was found to be 1.1. Thyroid doses ranged from 20 to 80 mGy. Comparison showed no statistical significance (p = 0.18). In addition, the average of surface dose variation along the z-axis in helical scans was studied and found to range between 5% (in 10 cm diameter phantom/24 mm collimation/pitch 1.0) and 8% (in 16 cm diameter phantom/12 mm collimation/pitch 0.7). We conclude that surface dose is an acceptable predictor for pediatric thyroid dose from CT. The uncertainty due to surface dose variability may be reduced if narrower collimation is used with a pitch factor close to 1.0. Also, the results did not show any effect of thyroid depth on the measured dose.
本研究旨在探讨通过测量颈部表面剂量来估算儿童 CT 甲状腺剂量的可能性。使用光激励发光剂量计测量了 25 名年龄在 1 至 3 岁之间的儿童的颈部表面剂量。测量了每个儿童的颈围。使用不同尺寸的丙烯酸体模和不同深度的孔研究了获得的表面剂量与甲状腺剂量之间的关系。使用孔-表面剂量比将患者的表面剂量转换为甲状腺剂量。使用适当的年龄校正因子后,利用 ImPACT 软件计算甲状腺剂量。采用配对 t 检验比较了我们的方法和 ImPACT 计算的甲状腺剂量。发现甲状腺与表面剂量的比值为 1.1。甲状腺剂量范围为 20 至 80 mGy。比较无统计学意义(p = 0.18)。此外,研究了螺旋扫描中 z 轴上表面剂量的变化,发现其范围在 5%(在 10cm 直径体模/24mm 准直/1.0 螺距)和 8%(在 16cm 直径体模/12mm 准直/0.7 螺距)之间。我们得出结论,表面剂量是 CT 儿童甲状腺剂量的可接受预测因子。如果使用接近 1.0 的螺距因子进行更窄的准直,则可以减少由于表面剂量变化引起的不确定性。此外,结果并未显示甲状腺深度对测量剂量的任何影响。