自闭症谱系障碍青少年情绪面孔加工的眼动、自主和电生理相关性。
Eye-tracking, autonomic, and electrophysiological correlates of emotional face processing in adolescents with autism spectrum disorder.
机构信息
Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn Street, Boston, MA 02215, USA.
出版信息
J Autism Dev Disord. 2013 Jan;43(1):188-99. doi: 10.1007/s10803-012-1565-1.
Abstract
Individuals with autism spectrum disorder (ASD) often have difficulty with social-emotional cues. This study examined the neural, behavioral, and autonomic correlates of emotional face processing in adolescents with ASD and typical development (TD) using eye-tracking and event-related potentials (ERPs) across two different paradigms. Scanning of faces was similar across groups in the first task, but the second task found that face-sensitive ERPs varied with emotional expressions only in TD. Further, ASD showed enhanced neural responding to non-social stimuli. In TD only, attention to eyes during eye-tracking related to faster face-sensitive ERPs in a separate task; in ASD, a significant positive association was found between autonomic activity and attention to mouths. Overall, ASD showed an atypical pattern of emotional face processing, with reduced neural differentiation between emotions and a reduced relationship between gaze behavior and neural processing of faces.
摘要
自闭症谱系障碍（ASD）患者通常在社交情感线索方面存在困难。本研究使用眼动追踪和事件相关电位（ERP）技术，在两个不同的范式中，分别检查了 ASD 青少年和典型发育（TD）青少年在情绪面孔处理方面的神经、行为和自主神经相关指标。在第一个任务中，两组在扫描面部时表现相似，但在第二个任务中发现，只有 TD 组的情绪相关 ERP 会随情绪表达而变化。此外，ASD 对非社交刺激的神经反应增强。只有在 TD 中，眼动追踪时对眼睛的注意力与在另一个任务中更快的面孔敏感 ERP 相关；而在 ASD 中，自主活动与对嘴巴的注意力之间存在显著的正相关关系。总的来说，ASD 表现出一种非典型的情绪面孔处理模式，情绪之间的神经分化减少，以及注视行为与面孔神经处理之间的关系减少。
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本文引用的文献
1
Pupillometry: A Window to the Preconscious?瞳孔测量学：潜意识的窗口？
Perspect Psychol Sci. 2012 Jan;7(1):18-27. doi: 10.1177/1745691611427305. Epub 2012 Jan 5.
2
Can gaze avoidance explain why individuals with Asperger's syndrome can't recognise emotions from facial expressions?目光回避能否解释为什么阿斯伯格综合征患者无法从面部表情识别情绪？
J Autism Dev Disord. 2012 Apr;42(4):606-18. doi: 10.1007/s10803-011-1283-0.
3
Developmental and individual differences on the P1 and N170 ERP components in children with and without autism.患有和未患自闭症儿童在P1和N170事件相关电位成分上的发育及个体差异。
Dev Neuropsychol. 2011;36(2):214-36. doi: 10.1080/87565641.2010.549870.
4
Electrophysiological Studies of Face Perception in Humans.人类面部感知的电生理研究
J Cogn Neurosci. 1996 Nov;8(6):551-565. doi: 10.1162/jocn.1996.8.6.551.
5
Patterns of visual attention to faces and objects in autism spectrum disorder.自闭症谱系障碍患者对面部和物体视觉注意力的模式。
J Autism Dev Disord. 2011 Feb;41(2):148-57. doi: 10.1007/s10803-010-1033-8.
6
Response to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders.自闭症谱系障碍成人对熟悉面孔、新熟悉面孔和新面孔的反应，通过事件相关电位（ERP）评估，是完整的。
Int J Psychophysiol. 2010 Aug;77(2):106-17. doi: 10.1016/j.ijpsycho.2010.04.011. Epub 2010 May 7.
7
Better working memory for non-social targets in infant siblings of children with Autism Spectrum Disorder.自闭症谱系障碍儿童的同胞婴儿对非社交目标的工作记忆更好。
Dev Sci. 2010 Jan 1;13(1):244-51. doi: 10.1111/j.1467-7687.2009.00882.x.
8
Emotion recognition in children with autism spectrum disorders: relations to eye gaze and autonomic state.自闭症谱系障碍儿童的情绪识别：与目光注视和自主状态的关系。
J Autism Dev Disord. 2010 Mar;40(3):358-70. doi: 10.1007/s10803-009-0884-3.
9
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Biol Psychiatry. 2009 Nov 15;66(10):950-7. doi: 10.1016/j.biopsych.2009.07.031. Epub 2009 Sep 18.
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Child Dev. 2009 Jul-Aug;80(4):1118-33. doi: 10.1111/j.1467-8624.2009.01320.x.
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