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自闭症谱系障碍儿童的同胞婴儿对非社交目标的工作记忆更好。

Better working memory for non-social targets in infant siblings of children with Autism Spectrum Disorder.

机构信息

Department of Psychology and Human Development, Peabody, Box #552, 230 Appleton Place, Vanderbilt University, Nashville, TN 37203-5701, USA.

出版信息

Dev Sci. 2010 Jan 1;13(1):244-51. doi: 10.1111/j.1467-7687.2009.00882.x.

Abstract

We compared working memory (WM) for the location of social versus non-social targets in infant siblings of children with Autism Spectrum Disorders (sibs-ASD, n = 25) and of typically developing children (sibs-TD, n = 30) at 6.5 and 9 months of age. There was a significant interaction of risk group and target type on WM, in which the sibs-ASD had better WM for non-social targets as compared with controls. There was no group by stimulus interaction on two non-memory measures. The results suggest that the increased competency of sibs-ASD in WM (creating, updating and using transient representations) for non-social stimuli distinguishes them from sibs-TD by 9 months of age. This early emerging strength is discussed as a developmental pathway that may have implications for social attention and learning in children at risk for ASD.

摘要

我们比较了自闭症谱系障碍儿童(ASD)同胞(sibs-ASD,n=25)和正常发育儿童(sibs-TD,n=30)在 6.5 个月和 9 个月大时对社交和非社交目标位置的工作记忆(WM)。WM 存在风险组和目标类型的显著交互作用,其中 sibs-ASD 对非社交目标的 WM 明显优于对照组。在两个非记忆测量上没有组与刺激的交互作用。结果表明,sibs-ASD 在 WM(创建、更新和使用瞬态表示)方面对非社交刺激的增强能力在 9 个月大时将其与 sibs-TD 区分开来。这种早期出现的优势被认为是一种发展途径,可能对自闭症谱系障碍风险儿童的社会注意力和学习有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ed/2818009/b548cbc63932/nihms122294f1a.jpg

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