自闭症谱系障碍儿童的面孔异常脱离及其对视眼动控制的调节。
Atypical disengagement from faces and its modulation by the control of eye fixation in children with autism spectrum disorder.
机构信息
Department of Cognitive and Behavioral Science, Graduate School of Arts and Sciences, University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.
出版信息
J Autism Dev Disord. 2011 May;41(5):629-45. doi: 10.1007/s10803-010-1082-z.
Abstract
By using the gap overlap task, we investigated disengagement from faces and objects in children (9-17 years old) with and without autism spectrum disorder (ASD) and its neurophysiological correlates. In typically developing (TD) children, faces elicited larger gap effect, an index of attentional engagement, and larger saccade-related event-related potentials (ERPs), compared to objects. In children with ASD, by contrast, neither gap effect nor ERPs differ between faces and objects. Follow-up experiments demonstrated that instructed fixation on the eyes induces larger gap effect for faces in children with ASD, whereas instructed fixation on the mouth can disrupt larger gap effect in TD children. These results suggest a critical role of eye fixation on attentional engagement to faces in both groups.
摘要
通过使用间隙重叠任务，我们研究了自闭症谱系障碍（ASD）儿童和非自闭症谱系障碍儿童（9-17 岁）对人脸和物体的注意力脱离情况，及其神经生理学相关性。与物体相比，在典型发育（TD）儿童中，人脸引发了更大的间隙效应，这是注意力投入的一个指标，并且引发了更大的与扫视相关的事件相关电位（ERPs）。相比之下，在患有 ASD 的儿童中，间隙效应和 ERPs 都没有在人脸和物体之间存在差异。后续实验表明，指示注视眼睛会在 ASD 儿童中引起更大的人脸间隙效应，而指示注视嘴巴会干扰 TD 儿童中的更大间隙效应。这些结果表明，眼睛注视在两组人群对面部注意力投入中起着关键作用。
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