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菲律宾女性的腰围与高血压和糖尿病前期风险。

Waist circumference and the risk of hypertension and prediabetes among Filipino women.

机构信息

USC Office of Population Studies Foundation, Talamban Campus, Cebu City, Philippines.

出版信息

Eur J Nutr. 2013 Mar;52(2):825-32. doi: 10.1007/s00394-012-0390-9. Epub 2012 Jun 9.

Abstract

OBJECTIVES

To examine waist circumference as a risk factor for having hypertension only, impaired fasting glucose only, or both hypertension and impaired fasting glucose, and assess whether the associations vary according to overweight status. Furthermore, optimal cut-offs for waist circumference in overweight women and non-overweight women were explored.

DATA AND METHODS

Data from 1,871 women aged 35-68 years in the 2005 Cebu Longitudinal Health and Nutrition Survey were used. Multinomial logistic regressions were used to model how waist circumference influenced the likelihood of having the three illness categories compared to having neither condition. Waist circumference cut-offs were explored using receiver operating characteristic analysis.

RESULTS

Adjusted for age and other confounders, each cm increase in waist circumference increased the odds of hypertension by 5 % for non-overweight women and 3 % for overweight women; impaired fasting glucose by 9 and 3 % for non-overweight and overweight women, respectively; and hypertension and impaired fasting glucose by 17 % among non-overweight versus 9 % for overweight women. Waist circumference cut-offs for non-overweight women were lower than overweight women.

CONCLUSION

Waist circumference was significantly associated with impaired fasting glucose and both hypertension and impaired fasting glucose, and the associations vary by overweight status.

摘要

目的

检验腰围是高血压、单纯空腹血糖受损或高血压合并空腹血糖受损的危险因素,并评估超重状态是否会影响这种关联。此外,还探讨了超重和非超重女性腰围的最佳切点。

方法

本研究使用了 2005 年宿务纵向健康和营养调查中 1871 名年龄在 35-68 岁的女性的数据。采用多项逻辑回归模型,分析腰围对三种疾病状态的影响,与无上述两种或三种疾病状态的人群相比。使用受试者工作特征曲线分析探索腰围的最佳切点。

结果

校正年龄和其他混杂因素后,对于非超重女性,腰围每增加 1 厘米,高血压的发生风险增加 5 %;对于超重女性,高血压的发生风险增加 3 %。对于非超重女性,空腹血糖受损的发生风险增加 9 %;对于超重女性,空腹血糖受损的发生风险增加 3 %。与超重女性相比,非超重女性的腰围切点较低。

结论

腰围与空腹血糖受损和高血压合并空腹血糖受损显著相关,且这种关联受超重状态的影响。

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