Department of Surgery, Division of Surgical Oncology, University of California at Davis, Sacramento, CA, USA.
Med Oncol. 2012 Dec;29(5):3250-7. doi: 10.1007/s12032-012-0266-0. Epub 2012 Jun 9.
We hypothesized that breast cancer (BCa) patients in urban counties would have higher rates of post-lumpectomy radiation therapy (RT) relative to patients in near-metro and rural counties. We used the Surveillance, Epidemiology, and End Results (SEER) database to identify women diagnosed with BCa treated with lumpectomy in the Sacramento area between 2000 and 2006. Patient counties were categorized as urban and near-metro. Multivariate logistic regression models predicted treatment with RT. Likelihood of undergoing RT was reported as odds ratios (OR) with 95 % confidence intervals (CI). Of 7,953 patients meeting entry criteria, 5,858 (73.7 %) underwent RT. On multivariate analysis, patients from near-metro (OR, 0.66; CI, 0.59-0.75; P < 0.001) and rural (OR 0.39, CI 0.30-0.52; P < 0.001) areas had a decreased likelihood of undergoing RT relative to patients from urban areas. Patients from near-metro and rural areas are less likely to receive RT following lumpectomy for BCa than their urban counterparts.
我们假设城市县的乳腺癌（BCa）患者接受保乳手术后放射治疗（RT）的比例相对较高，而近都会和农村县的患者则较低。我们使用监测、流行病学和最终结果（SEER）数据库，确定了 2000 年至 2006 年间在萨克拉门托地区接受保乳术治疗的 BCa 女性患者。将患者的县分为城市和近都会。多变量逻辑回归模型预测了 RT 治疗。RT 治疗的可能性以优势比（OR）及其 95%置信区间（CI）表示。在符合入选标准的 7953 名患者中，5858 名（73.7%）接受了 RT。多变量分析显示，来自近都会区（OR，0.66；CI，0.59-0.75；P<0.001）和农村区（OR，0.39；CI，0.30-0.52；P<0.001）的患者接受 RT 的可能性低于来自城市地区的患者。与城市地区的患者相比，近都会区和农村地区的 BCa 患者在接受保乳手术后接受 RT 的可能性较低。
