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甲状腺内甲状旁腺腺瘤伴慢性淋巴细胞性甲状腺炎所致原发性甲状旁腺功能亢进症。

Primary hyperparathyroidism due to an intrathyroidal parathyroid adenoma associated with chronic lymphocytic thyroiditis.

作者信息

Cating-Cabral Monica Therese, Cabungcal Arsenio Claro, Villafuerte Cesar Vincent, Añel-Quimpo Joselynna

机构信息

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of the Philippines, Philippine General Hospital, Manila, Philippines.

出版信息

BMJ Case Rep. 2012 Jun 8;2012:bcr2012006198. doi: 10.1136/bcr-2012-006198.

Abstract

This is a case of a 44-year-old woman with an anterior neck mass and hypothyroidism who presented with an incidental finding of an elevated serum calcium level and was found to have primary hyperparathyroidism and osteoporosis. During surgical exploration no parathyroid adenoma was found, although a nodule was palpated within the right thyroid lobe. Examination of the excised right thyroid lobe revealed an intrathyroidal parathyroid adenoma and chronic lymphocytic thyroiditis. After surgery, she did not develop severe hypocalcaemia and this was attributed to preoperative treatment with pamidronate. In the months following surgery, parathyroid hormone remained undetectable.

摘要

这是一例44岁女性患者,有颈部前方肿物及甲状腺功能减退,偶然发现血清钙水平升高,诊断为原发性甲状旁腺功能亢进症和骨质疏松症。手术探查时未发现甲状旁腺腺瘤,尽管在右侧甲状腺叶内可触及一个小结节。对切除的右侧甲状腺叶进行检查发现甲状腺内甲状旁腺腺瘤及慢性淋巴细胞性甲状腺炎。术后,她未发生严重低钙血症,这归因于术前使用帕米膦酸治疗。术后数月,甲状旁腺激素仍检测不到。

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本文引用的文献

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Anatomy and embryology of the thyroid and parathyroid glands.甲状腺及甲状旁腺的解剖学与胚胎学
Semin Ultrasound CT MR. 2012 Apr;33(2):104-14. doi: 10.1053/j.sult.2011.12.005.
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Clinical practice. Primary hyperparathyroidism.临床实践。原发性甲状旁腺功能亢进症。
N Engl J Med. 2011 Dec 22;365(25):2389-97. doi: 10.1056/NEJMcp1106636.
10
Primary hyperparathyroidism: an update.原发性甲状旁腺功能亢进症:更新。
Curr Opin Endocrinol Diabetes Obes. 2010 Dec;17(6):554-60. doi: 10.1097/MED.0b013e32833f47e4.

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