Department of Pediatrics, St. John's Medical College Hospital, Bangalore, India.
Trop Med Int Health. 2012 Aug;17(8):962-71. doi: 10.1111/j.1365-3156.2012.03022.x. Epub 2012 Jun 12.
To understand the health status of HIV orphans in a well-structured institutional facility in India.
Prospective longitudinal analysis of growth and anaemia prevalence among these children, between June 2008 and May 2011.
A total of 85 HIV-infected orphan children residing at Sneha Care Home, Bangalore, for at least 1 year, were included in the analysis. Prevalence of anaemia at entry into the home was 40%, with the cumulative incidence of anaemia during the study period being 85%. At baseline, 79% were underweight and 72% were stunted. All children, irrespective of their antiretroviral therapy (ART) status, showed an improvement in nutritional status over time as demonstrated by a significant increase in weight (median weight-for-age Z-score: -2.75 to -1.74, P < 0.001) and height Z-scores (median height-for-age Z-score: -2.69 to -1.63, P < 0.001).
These findings suggest that good nutrition even in the absence of ART can bring about improvement in growth. The Sneha Care Home model indicates that the holistic approach used in the Home may have been helpful in combating HIV and poor nutritional status in severely malnourished orphaned children.
了解印度一家结构完善的机构收容所中艾滋病毒孤儿的健康状况。
对这些儿童 2008 年 6 月至 2011 年 5 月期间的生长和贫血患病率进行前瞻性纵向分析。
共纳入 85 名居住在班加罗尔 Sneha 关爱之家至少 1 年的感染艾滋病毒的孤儿儿童。进入收容所时贫血患病率为 40%,研究期间贫血的累积发病率为 85%。基线时,79%的儿童体重不足,72%的儿童发育迟缓。所有儿童,无论其抗逆转录病毒治疗(ART)状况如何,随着时间的推移其营养状况均有所改善,表现为体重(体重年龄 Z 评分中位数:-2.75 至-1.74,P<0.001)和身高 Z 评分(身高年龄 Z 评分中位数:-2.69 至-1.63,P<0.001)显著增加。
这些发现表明,即使没有 ART,良好的营养也可以促进生长。Sneha 关爱之家模式表明,该模式在家庭中采用的整体方法可能有助于对抗 HIV 和严重营养不良的孤儿儿童的不良营养状况。