Yabusaki Hiroshi, Nashimoto Atsushi, Matsuki Atsushi, Aizawa Masaki
Department of Surgery, Niigata Cancer Center Hospital, Niigata, Japan.
Hepatogastroenterology. 2012 Oct;59(119):2032-6. doi: 10.5754/hge12392.
BACKGROUND/AIMS: Proximal gastrectomy has two problems, reflux esophagitis and curability. This study evaluates postoperative outcomes focusing on reflux esophagitis and curability of proximal gastrectomy with jejunal pouch interposition for early gastric cancer in the upper third of the stomach.
One hundred and thirty nine patients who underwent jejunal pouch interposition between 1996 and 2011, 10 esophago-gastrostomy and 20 jejunal interposition at our institution were compared retrospectively to examine heart burn and reflux esophagitis. Furthermore, we examined the remote outcomes of jejunal pouch interposition patients.
There were significantly fewer cases of heart burn; the numbers of cases of reflux esophagitis based on endoscopic findings were significantly small in jejunal pouch interposition. Carcinoma of the remnant stomach after jejunal pouch interposition was observed in 9 patients, curative treatment was possible with endoscopic therapy in 6 patients and surgical treatment in 3 patients. There are 119 survivals and 20 deaths at present Death caused primary disease is only 2 patients. Both recurrent patterns were peritoneal metastasis and the histopathological diagnosis was not indicated for proximal gastrectomy.
Jejunal pouch interposition after proximal gastrectomy for early upper third gastric cancer proves beneficial and favorable modality achieving prevention of reflux esophagitis and high curability.
背景/目的:近端胃切除术存在两个问题,即反流性食管炎和根治性。本研究评估了采用空肠袋插入术治疗胃上部三分之一早期胃癌的近端胃切除术后的结局,重点关注反流性食管炎和根治性。
回顾性比较了1996年至2011年间在我院接受空肠袋插入术的139例患者、10例行食管胃吻合术的患者和20例行空肠插入术的患者,以检查烧心和反流性食管炎情况。此外,我们还检查了空肠袋插入术患者的远期结局。
烧心病例明显较少;基于内镜检查结果的反流性食管炎病例数在空肠袋插入术中明显较少。空肠袋插入术后残胃癌患者有9例,其中6例可行内镜治疗,3例需手术治疗。目前有119例存活,20例死亡。因原发性疾病死亡的仅2例。两种复发模式均为腹膜转移,且近端胃切除术的组织病理学诊断未明确。
对于胃上部三分之一早期胃癌,近端胃切除术后行空肠袋插入术是一种有益且良好的术式,可预防反流性食管炎并实现高根治性。