• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

候选基因和 QTL 区域中单核苷酸多态性(SNP)标记与商品猪肉质性状的关联。

Association of single nucleotide polymorphism (SNP) markers in candidate genes and QTL regions with pork quality traits in commercial pigs.

机构信息

USDA, ARS, U.S. Meat Animal Research Center, Spur 18D, Clay Center, NE 68933-0166, USA.

出版信息

Meat Sci. 2012 Dec;92(4):511-8. doi: 10.1016/j.meatsci.2012.05.020. Epub 2012 May 25.

DOI:10.1016/j.meatsci.2012.05.020
PMID:22688438
Abstract

Numerous reports have described genetic markers or genomic regions (QTL) associated with pork quality and/or palatability but few validation studies have been reported. Therefore, 156 SNP markers from 45 candidate genes and eight QTL regions were analyzed for association with pork quality and palatability traits from 888 pork loins. Loins were collected at three slaughter facilities and selected to represent a wide range of pork color, pH and marbling. Phenotypic data recorded included objective and subjective measures of color and marbling, purge loss, shear force, and cooking loss. Data were analyzed with SAS PROC MIXED where loin was fit as a random effect. Results indicated some of the markers tested should be useful in industry, while others are not segregating in all populations or linkage disequilibrium between markers and causative genetic variation fluctuates among populations limiting their universal utility. Genes with the largest effects on pork quality were MC4R, IGF2, CAST and PRKAG3.

摘要

大量报道描述了与猪肉品质和/或口感相关的遗传标记或基因组区域(QTL),但很少有验证研究报道。因此,从 888 个猪腰肉中分析了来自 45 个候选基因和 8 个 QTL 区域的 156 个 SNP 标记与猪肉品质和口感特性的关联。这些腰肉取自三个屠宰场,并进行了选择,以代表广泛的猪肉颜色、pH 值和大理石纹。记录的表型数据包括颜色和大理石纹的客观和主观测量、渗出损失、剪切力和烹饪损失。使用 SAS PROC MIXED 分析数据,其中将腰肉拟合为随机效应。结果表明,测试的一些标记物在工业中应该是有用的,而其他标记物在所有群体中没有分离,或者标记物与致病遗传变异之间的连锁不平衡在群体之间波动,限制了它们的普遍适用性。对猪肉品质影响最大的基因是 MC4R、IGF2、CAST 和 PRKAG3。

相似文献

1
Association of single nucleotide polymorphism (SNP) markers in candidate genes and QTL regions with pork quality traits in commercial pigs.候选基因和 QTL 区域中单核苷酸多态性(SNP)标记与商品猪肉质性状的关联。
Meat Sci. 2012 Dec;92(4):511-8. doi: 10.1016/j.meatsci.2012.05.020. Epub 2012 May 25.
2
PRKAG3 and CAST genetic polymorphisms and quality traits of dry-cured hams--I. Associations in Spanish dry-cured ham Jamón Serrano.PRKAG3 和 CAST 基因多态性与干腌火腿品质特性——I. 西班牙干腌火腿 Serrano Ham 的关联。
Meat Sci. 2012 Dec;92(4):346-53. doi: 10.1016/j.meatsci.2012.06.018. Epub 2012 Jun 18.
3
Predictive markers in calpastatin for tenderness in commercial pig populations.商业猪群中钙蛋白酶抑制蛋白的嫩度预测标记物。
J Anim Sci. 2011 Sep;89(9):2663-72. doi: 10.2527/jas.2010-3556. Epub 2011 Mar 31.
4
The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in pigs: evidence from the effects of a cathepsin D (CTSD) gene polymorphism.胰岛素样生长因子 2 (IGF2) 基因内含子 3-g.3072G>A 多态性并非唯一影响猪肌肉生长和胴体性状的Sus scrofa 染色体 2p 突变:来自组织蛋白酶 D (CTSD) 基因多态性影响的证据。
J Anim Sci. 2010 Jul;88(7):2235-45. doi: 10.2527/jas.2009-2560. Epub 2010 Apr 9.
5
Genome-wide association studies (GWAS) identify a QTL close to PRKAG3 affecting meat pH and colour in crossbred commercial pigs.全基因组关联研究(GWAS)在杂交商品猪中鉴定出一个与PRKAG3基因相近的数量性状位点(QTL),该位点影响猪肉的pH值和色泽。
BMC Genet. 2015 Apr 7;16:33. doi: 10.1186/s12863-015-0192-1.
6
Association of polymorphisms in candidate genes with colour, water-holding capacity, and composition traits in bovine M. longissimus and M. semimembranosus.候选基因多态性与牛背最长肌和半膜肌颜色、持水力和组成特性的关联。
Meat Sci. 2010 Oct;86(2):270-5. doi: 10.1016/j.meatsci.2010.04.013. Epub 2010 Apr 28.
7
Evaluation of QTL for carcass merit and meat quality traits in a US commercial Duroc population.评估美国商业杜洛克猪群体的胴体肉质性状 QTL。
Meat Sci. 2012 Oct;92(2):132-8. doi: 10.1016/j.meatsci.2012.04.023. Epub 2012 Apr 21.
8
PRKAG3 and CAST genetic polymorphisms and quality traits of dry-cured hams--II. Associations in French dry-cured ham Jambon de Bayonne and their dependence on salt reduction.PRKAG3 和 CAST 基因多态性与干腌火腿品质特性——Ⅱ.法国干腌火腿 Bayonne 的关联及其对盐度降低的依赖性。
Meat Sci. 2012 Dec;92(4):354-9. doi: 10.1016/j.meatsci.2012.06.022. Epub 2012 Jun 19.
9
PRKAG3 and CAST genetic polymorphisms and quality traits of dry-cured hams--III. Associations in Slovenian dry-cured ham Kraški pršut and their dependence on processing.PRKAG3 和 CAST 基因多态性与干腌火腿品质特性——III. 斯洛文尼亚干腌火腿 Kraški pršut 中的关联及其与加工的关系。
Meat Sci. 2012 Dec;92(4):360-5. doi: 10.1016/j.meatsci.2012.06.021. Epub 2012 Jun 23.
10
Genome-wide association of meat quality traits and tenderness in swine.猪肌肉品质和嫩度的全基因组关联分析。
J Anim Sci. 2013 Sep;91(9):4043-50. doi: 10.2527/jas.2013-6255. Epub 2013 Aug 13.

引用本文的文献

1
Single Nucleotide Polymorphisms of Leptin and Calpain/Calpastatin in Key Traits of Pork Meat Quality.瘦素与钙蛋白酶/钙蛋白酶抑制蛋白的单核苷酸多态性与猪肉肉质关键性状的关系
Animals (Basel). 2025 Aug 4;15(15):2270. doi: 10.3390/ani15152270.
2
The Effect of rs80860411 Polymorphism on Fattening, Slaughter, and Pork Quality Traits in Polish Large White and Pulawska Breeds.rs80860411多态性对波兰大白猪和普拉瓦斯卡猪育肥、屠宰及猪肉品质性状的影响。
Animals (Basel). 2025 Jul 15;15(14):2090. doi: 10.3390/ani15142090.
3
Enhancement of porcine intramuscular fat content by overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase in skeletal muscle.
通过在骨骼肌中过表达细胞质形式的磷酸烯醇丙酮酸羧激酶来提高猪的肌内脂肪含量。
Sci Rep. 2017 Mar 2;7:43746. doi: 10.1038/srep43746.
4
Whole-genome association analysis of pork meat pH revealed three significant regions and several potential genes in Finnish Yorkshire pigs.猪肉pH值的全基因组关联分析揭示了芬兰约克夏猪的三个显著区域和几个潜在基因。
BMC Genet. 2017 Feb 13;18(1):13. doi: 10.1186/s12863-017-0482-x.
5
Relationships between Single Nucleotide Polymorphism Markers and Meat Quality Traits of Duroc Breeding Stocks in Korea.韩国杜洛克种猪单核苷酸多态性标记与肉质性状的关系
Asian-Australas J Anim Sci. 2016 Sep;29(9):1229-38. doi: 10.5713/ajas.16.0158. Epub 2016 Aug 10.
6
Genome Wide Association Studies (GWAS) Identify QTL on SSC2 and SSC17 Affecting Loin Peak Shear Force in Crossbred Commercial Pigs.全基因组关联研究(GWAS)确定了猪2号和17号染色体上影响杂种商品猪腰峰剪切力的数量性状位点(QTL)。
PLoS One. 2016 Feb 22;11(2):e0145082. doi: 10.1371/journal.pone.0145082. eCollection 2016.
7
Genome-wide QTL analysis of meat quality-related traits in a large F2 intercross between Landrace and Korean native pigs.长白猪与韩国本土猪大型F2杂交群体中肉质相关性状的全基因组QTL分析。
Genet Sel Evol. 2015 Feb 22;47(1):7. doi: 10.1186/s12711-014-0080-6.
8
Genome-wide association studies (GWAS) identify a QTL close to PRKAG3 affecting meat pH and colour in crossbred commercial pigs.全基因组关联研究(GWAS)在杂交商品猪中鉴定出一个与PRKAG3基因相近的数量性状位点(QTL),该位点影响猪肉的pH值和色泽。
BMC Genet. 2015 Apr 7;16:33. doi: 10.1186/s12863-015-0192-1.
9
Polymorphisms in epigenetic and meat quality related genes in fourteen cattle breeds and association with beef quality and carcass traits.14个牛品种中表观遗传和肉质相关基因的多态性及其与牛肉品质和胴体性状的关联
Asian-Australas J Anim Sci. 2015 Apr;28(4):467-75. doi: 10.5713/ajas.13.0837.
10
A combination of two variants in PRKAG3 is needed for a positive effect on meat quality in pigs.两种 PRKAG3 变异的组合对猪肉质产生积极影响是必需的。
BMC Genet. 2014 Feb 28;15:29. doi: 10.1186/1471-2156-15-29.