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肉瘤样肾细胞癌:一例报告及文献综述

Sarcomatoid renal cell carcinoma: a case report and literature review.

作者信息

Reiter Michael, Schwope Ryan, Clarkson Arthur

机构信息

Department of Radiology, Brooke Army Medical Center, San Antonio, TX 78234, USA.

出版信息

J Radiol Case Rep. 2012 Apr;6(4):11-6. doi: 10.3941/jrcr.v6i4.976. Epub 2012 Apr 1.

DOI:10.3941/jrcr.v6i4.976
PMID:22690291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3370693/
Abstract

Renal cell carcinoma (RCC) is the most common malignancy of the kidney and consists of multiple subtypes. The sarcomatoid variety, while previously considered a distinct histologic subtype, is now categorized as a form of dedifferentiated carcinoma. When present, it is associated with a significant decrease in patient survival due to its rapid growth and intrusive behavior. Preoperative knowledge of this diagnosis may be beneficial to clinicians in order to modify treatment options and follow-up protocols. This report describes a case of sarcomatoid renal cell carcinoma in which the patient initially presented with flank pain. We then discuss the clinical features of sarcomatoid renal cell carcinoma and its imaging appearance on computed tomography (CT), and succinctly review the subtypes of renal cell carcinoma and their imaging characteristics.

摘要

肾细胞癌(RCC)是最常见的肾脏恶性肿瘤,由多种亚型组成。肉瘤样变体虽然以前被认为是一种独特的组织学亚型,但现在被归类为去分化癌的一种形式。一旦出现,由于其快速生长和侵袭性行为,会导致患者生存率显著下降。术前了解这一诊断可能对临床医生有益,以便修改治疗方案和随访方案。本报告描述了一例肉瘤样肾细胞癌病例,该患者最初表现为侧腹痛。然后我们讨论肉瘤样肾细胞癌的临床特征及其在计算机断层扫描(CT)上的影像学表现,并简要回顾肾细胞癌的亚型及其影像学特征。

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本文引用的文献

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MRI findings of sarcomatoid renal cell carcinoma in nine cases.MRI 表现:9 例肉瘤样肾细胞癌的分析。
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Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation.肾细胞癌常见和不常见的组织学亚型:影像学表现与病理对照
Radiographics. 2006 Nov-Dec;26(6):1795-806; discussion 1806-10. doi: 10.1148/rg.266065010.
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2004 WHO classification of the renal tumors of the adults.2004年世界卫生组织成人肾肿瘤分类
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Sarcomatoid differentiation in renal cell carcinoma: prognostic implications.
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Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma.针对肉瘤样和快速进展性肾细胞癌的积极化疗。
Cancer. 2004 Oct 1;101(7):1545-51. doi: 10.1002/cncr.20541.