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肉瘤样肾细胞癌:一例报告及文献综述

Sarcomatoid renal cell carcinoma: a case report and literature review.

作者信息

Reiter Michael, Schwope Ryan, Clarkson Arthur

机构信息

Department of Radiology, Brooke Army Medical Center, San Antonio, TX 78234, USA.

出版信息

J Radiol Case Rep. 2012 Apr;6(4):11-6. doi: 10.3941/jrcr.v6i4.976. Epub 2012 Apr 1.

Abstract

Renal cell carcinoma (RCC) is the most common malignancy of the kidney and consists of multiple subtypes. The sarcomatoid variety, while previously considered a distinct histologic subtype, is now categorized as a form of dedifferentiated carcinoma. When present, it is associated with a significant decrease in patient survival due to its rapid growth and intrusive behavior. Preoperative knowledge of this diagnosis may be beneficial to clinicians in order to modify treatment options and follow-up protocols. This report describes a case of sarcomatoid renal cell carcinoma in which the patient initially presented with flank pain. We then discuss the clinical features of sarcomatoid renal cell carcinoma and its imaging appearance on computed tomography (CT), and succinctly review the subtypes of renal cell carcinoma and their imaging characteristics.

摘要

肾细胞癌(RCC)是最常见的肾脏恶性肿瘤,由多种亚型组成。肉瘤样变体虽然以前被认为是一种独特的组织学亚型,但现在被归类为去分化癌的一种形式。一旦出现,由于其快速生长和侵袭性行为,会导致患者生存率显著下降。术前了解这一诊断可能对临床医生有益,以便修改治疗方案和随访方案。本报告描述了一例肉瘤样肾细胞癌病例,该患者最初表现为侧腹痛。然后我们讨论肉瘤样肾细胞癌的临床特征及其在计算机断层扫描(CT)上的影像学表现,并简要回顾肾细胞癌的亚型及其影像学特征。

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