Biban Paolo, Gaffuri Marcella, Spaggiari Stefania, Zaglia Federico, Serra Alessandra, Santuz Pierantonio
Department of Pediatrics, Pediatric and Neonatal intensive Care Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Pediatr Rep. 2012 Jan 2;4(1):e13. doi: 10.4081/pr.2012.e13. Epub 2012 Mar 26.
Septic shock remains a major cause of morbidity and mortality among children, mainly due to acute hemodynamic compromise and multiple organ failures. In the last decade, international guidelines for the management of septic shock, as well as clinical practice parameters for hemodynamic support of pediatric patients, have been published. Early recognition and aggressive therapy of septic shock, by means of abundant fluid resuscitation, use of catecholamines and other adjuvant drugs, are widely considered of pivotal importance to improve the short and long-term outcome of these patients. The aim of this paper is to summarize the modern approach to septic shock in children, particularly in its very initial phase, when pediatric healthcare providers may be required to intervene in the pre-intensive care unit setting or just on admission in the pediatric intensive care unit.
脓毒性休克仍然是儿童发病和死亡的主要原因，主要是由于急性血流动力学障碍和多器官功能衰竭。在过去十年中，已发布了脓毒性休克管理的国际指南以及儿科患者血流动力学支持的临床实践参数。通过充分的液体复苏、使用儿茶酚胺和其他辅助药物对脓毒性休克进行早期识别和积极治疗，被广泛认为对于改善这些患者的短期和长期预后至关重要。本文的目的是总结儿童脓毒性休克的现代治疗方法，特别是在其非常早期阶段，此时儿科医疗服务提供者可能需要在重症监护病房前环境或刚进入儿科重症监护病房时进行干预。
