University of British Columbia, BC Children's Hospital, Vancouver, BC, Canada.
Pediatr Crit Care Med. 2011 Sep;12(5):494-503. doi: 10.1097/PCC.0b013e318207096c.
According to World Health Organization estimates, sepsis accounts for 60%-80% of lost lives per year in childhood. Measures appropriate for resource-scarce and resource-abundant settings alike can reduce sepsis deaths. In this regard, the World Federation of Pediatric Intensive Care and Critical Care Societies Board of Directors announces the Global Pediatric Sepsis Initiative, a quality improvement program designed to improve quality of care for children with sepsis.
To announce the global sepsis initiative; to justify some of the bundles that are included; and to show some preliminary data and encourage participation.
The Global Pediatric Sepsis Initiative is developed as a Web-based education, demonstration, and pyramid bundles/checklist tool (http://www.pediatricsepsis.org or http://www.wfpiccs.org). Four health resource categories are included. Category A involves a nonindustrialized setting with mortality rate <5 yrs and >30 of 1,000 children. Category B involves a nonindustrialized setting with mortality rate <5 yrs and <30 of 1,000 children. Category C involves a developing industrialized nation. In category D, developed industrialized nation are determined and separate accompanying administrative and clinical parameters bundles or checklist quality improvement recommendations are provided, requiring greater resources and tasks as resource allocation increased from groups A to D, respectively.
In the vanguard phase, data for 361 children (category A, n = 34; category B, n = 12; category C, n = 84; category D, n = 231) were successfully entered, and quality-assurance reports were sent to the 23 participating international centers. Analysis of bundles for categories C and D showed that reduction in mortality was associated with compliance with the resuscitation (odds ratio, 0.369; 95% confidence interval, 0.188-0.724; p < .0004) and intensive care unit management (odds ratio, 0.277; 95% confidence interval, 0.096-0.80) bundles.
The World Federation of Pediatric Intensive Care and Critical Care Societies Global Pediatric Sepsis Initiative is online. Success in reducing pediatric mortality and morbidity, evaluated yearly as a measure of global child health care quality improvement, requires ongoing active recruitment of international participant centers. Please join us at http://www.pediatricsepsis.org or http://www.wfpiccs.org.
根据世界卫生组织的估计，每年全球有 60%-80%的儿童因败血症而死亡。在资源匮乏和资源丰富的环境中采取同样的措施，可以降低败血症的死亡率。为此，世界儿童重症监护和危重病学会联合会理事会宣布了全球儿科败血症倡议，这是一个旨在提高败血症患儿护理质量的质量改进项目。
宣布全球败血症倡议；说明其中一些包含的措施；展示一些初步数据并鼓励参与。
全球儿科败血症倡议是作为一个基于网络的教育、示范和金字塔式套餐/检查表工具（http://www.pediatricsepsis.org 或 http://www.wfpiccs.org）开发的。它包括四个卫生资源类别。A 类涉及死亡率<5 岁且>1000 名儿童中有 30 名以上的非工业化环境。B 类涉及死亡率<5 岁且<1000 名儿童中有 30 名的非工业化环境。C 类涉及发展中工业化国家。在 D 类中，发达国家分别确定，并提供单独的配套行政和临床参数套餐/检查表质量改进建议，随着资源分配从 A 组到 D 组的增加，分别需要更多的资源和任务。
在先锋阶段，成功输入了 361 名儿童的数据（A 类，n=34；B 类，n=12；C 类，n=84；D 类，n=231），并向 23 个参与的国际中心发送了质量保证报告。对 C 类和 D 类的套餐分析表明，死亡率的降低与复苏（优势比，0.369；95%置信区间，0.188-0.724；p<.0004）和重症监护病房管理（优势比，0.277；95%置信区间，0.096-0.80）套餐的依从性相关。
世界儿童重症监护和危重病学会联合会的全球儿科败血症倡议现已上线。每年作为衡量全球儿童保健质量改进的指标，成功降低儿科死亡率和发病率需要持续积极招募国际参与中心。请访问 http://www.pediatricsepsis.org 或 http://www.wfpiccs.org 与我们一起参与。
