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白玉兰和紫玉兰鲜花精油的化学成分和生物活性比较研究。

Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils.

机构信息

Chemistry Department, Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, 529 S. Jackson St., Louisville, KY 40202, USA.

出版信息

Nat Prod Res. 2013;27(12):1091-7. doi: 10.1080/14786419.2012.696256. Epub 2012 Jun 12.

Abstract

The biological activities and the determined major volatile components in the Magnolia grandiflora and M. virginiana flowers extracts were compared. Volatile components were detected in the essential oil by dynamic headspace sampling (HS). 2-Phenylethanol (40% and 61%) was found as the main constituent in the essential oil and HS samples of M. virginiana, respectively. In the M. grandiflora oil sample, (E,E)-farnesol (18%) and 2-phenylethanol (10%) were found as main constituents, whereas germacrene D (17%) and β-bisabolene (17%) were the main components of the HS sample. The essential oil in M. virginiana displayed a moderate antioxidant activity relative to vitamin E, whereas both essential oils were active against human lung carcinoma and breast carcinoma cell lines, even at concentrations higher than 200 µg mL(-1).

摘要

比较了白玉兰和红花玉兰花朵提取物的生物活性和确定的主要挥发性成分。通过动态顶空采样(HS)检测到精油中的挥发性成分。2-苯乙醇(40%和61%)分别被发现为红花玉兰精油和 HS 样品中的主要成分。在白玉兰油样中,(E,E)-法呢醇(18%)和 2-苯乙醇(10%)被发现为主要成分,而大根香叶烯 D(17%)和β-没药烯(17%)则是 HS 样品的主要成分。红花玉兰精油的抗氧化活性相对于维生素 E 为中等,而两种精油均对人肺癌和乳腺癌细胞系具有活性,即使在浓度高于 200μg/mL 时也是如此。

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