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急诊室收治的酒精中毒青少年的血清葡萄糖和电解质水平:一项未配对病例对照研究。

Serum glucose and electrolyte levels in alcohol-intoxicated adolescents on admission to the emergency department: an unmatched case-control study.

机构信息

Pediatric Emergency Department, Rambam Health Care Campus, POB 9602, Haifa 31096, Israel.

出版信息

Eur J Pediatr. 2012 Sep;171(9):1397-400. doi: 10.1007/s00431-012-1766-9. Epub 2012 Jun 13.

Abstract

Aimed at examining serum glucose and electrolytes concentrations in adolescents with acute alcohol intoxication (AAI) on admission to the pediatric Emergency Department (ED), a retrospective unmatched, case-control study was conducted. Two cohorts of adolescents were compared, patients presenting with AAI and patients presenting with non-alcohol intoxication. The study group included ED patients aged 12-18 years with AAI. The control group included ED patients aged 12-18 years who had poisoning from a non-illicit drug. Demographic characteristics and glucose and electrolyte blood levels were extracted from the medical files. The records of patients who were admitted between January 2007 and December 2009 were analyzed. The study group and the control group included 106 subjects and 27 subjects, respectively. The study subjects had serum ethanol levels in the range of 55.6-297 mg/dL. No case of hypoglycemia was recorded. The study subjects had higher glucose levels and lower potassium levels compared to the controls (p < 0.005 and p < 0.0001, respectively). No such difference was found when the levels of sodium and bicarbonate were compared (p = 0.3 and p = 0.14, respectively). In conclusion, the findings of this study suggest that at presentation to the ED adolescents with AAI are at low risk for hypoglycemia.

摘要

本研究旨在探讨儿科急诊就诊的急性酒精中毒(AAI)青少年的血清血糖和电解质浓度。采用回顾性非匹配病例对照研究方法。比较了两组青少年患者,一组为 AAI 患者,一组为非酒精中毒患者。研究组包括年龄在 12-18 岁、有 AAI 的 ED 患者。对照组包括年龄在 12-18 岁、因非非法药物中毒而就诊的 ED 患者。从病历中提取人口统计学特征和血糖及电解质血水平。分析了 2007 年 1 月至 2009 年 12 月期间入院的患者记录。研究组和对照组分别包括 106 例和 27 例患者。研究对象的血清乙醇水平在 55.6-297mg/dL 之间。未记录低血糖病例。与对照组相比,研究组的血糖水平更高,钾水平更低(p<0.005 和 p<0.0001)。比较钠和碳酸氢盐水平时未发现差异(p=0.3 和 p=0.14)。总之,本研究结果表明,在 ED 就诊的 AAI 青少年低血糖风险较低。

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