Daripally V K, Shah N S
Department of Geriatric Medicine, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, UK.
J R Coll Physicians Edinb. 2012 Jun;42(2):124-7. doi: 10.4997/JRCPE.2012.207.
Henoch-Schönlein purpura (HSP) is a small vessel vasculitis with immunoglobulin A-dominant immune deposits found in vessel walls. It primarily affects children, is uncommon in adults and often under-recognised in the elderly population due to its rarity in this group. When a purpuric rash develops in an older person it is typically treated with antibiotics for presumed infection, rather than investigated as potentially HSP. It is important to recognise this condition, particulary in older adults, as diagnosis has implications for management and prognosis. We report a case of vasculitis with renal involvement in an older person.
过敏性紫癜（HSP）是一种小血管血管炎，在血管壁中发现以免疫球蛋白A为主的免疫沉积物。它主要影响儿童，在成人中不常见，在老年人群中常常未被充分认识，因为在该群体中发病率较低。当老年人出现紫癜性皮疹时，通常会因推测为感染而使用抗生素治疗，而不是作为潜在的过敏性紫癜进行检查。认识到这种疾病很重要，特别是在老年人中，因为诊断对治疗和预后有影响。我们报告一例老年人血管炎伴肾脏受累的病例。
