Phechrmeekha Thanawuth, Sritularak Boonchoo, Likhitwitayawuid Kittisak
Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
J Asian Nat Prod Res. 2012;14(8):748-54. doi: 10.1080/10286020.2012.689979. Epub 2012 Jun 14.
Phytochemical investigation of the stem of Dendrobium capillipes resulted in the isolation of a new flavonol glycoside namely quercetin-3-O-α-L-rhamnopyranosyl-(1 → 2)-β-d-xylopyranoside, along with seven known phenolic compounds which included two flavonol glycosides and five bibenzyls. From the stem of Dendrobium secundum, a new compound named 5-hydroxy-3,4,3',4',5'-pentamethoxybibenzyl was characterized, together with two known bibenzyls and three glycosidic flavonoids. Some of the isolated bibenzyls showed cytotoxicity against KB, NCI-H187, and MCF-7 cancer cells, whereas all of the glycosidic flavonoids were devoid of activity.
对细叶石斛茎进行植物化学研究，分离得到一种新的黄酮醇苷，即槲皮素-3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-木吡喃糖苷，以及七种已知的酚类化合物，其中包括两种黄酮醇苷和五种联苄。从鼓槌石斛茎中鉴定出一种名为5-羟基-3,4,3',4',5'-五甲氧基联苄的新化合物，以及两种已知的联苄和三种糖苷类黄酮。一些分离得到的联苄对KB、NCI-H187和MCF-7癌细胞显示出细胞毒性，而所有糖苷类黄酮均无活性。
