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一种从唐古特碎米荠地上部分分离得到的新型酰化黄酮醇苷。

A new acylated flavonol glycoside from the aerial parts of Cardamine tangutorum.

作者信息

Feng Wei-Sheng, Zhang Qiu-Bo, Zheng Xiao-Ke, Chen Hui, Zhang Yan-Li, Zhang Chun-Lei

机构信息

School of Pharmaceutical Science, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China.

出版信息

J Asian Nat Prod Res. 2012;14(8):805-10. doi: 10.1080/10286020.2012.692363. Epub 2012 Jun 14.

Abstract

A new acylated flavonol glycoside, kaempferol-3-O-β-D-(2-feruloylglucopyranosyl) (1 → 6)-[β-D-glucopyranosyl(1 → 2)]-β-D-glucopyranoside, named tangutorumoside A (1), together with 12 known compounds, was isolated from 50% acetone extract of Cardamine tangutorum. Their structures were elucidated by NMR and MS experiments. In addition, compound 1 could promote the proliferation of splenic lymphocytes and thymic lymphocytes with ConA in vitro.

摘要

从碎米荠的50%丙酮提取物中分离得到一种新的酰化黄酮醇苷,山柰酚-3-O-β-D-(2-阿魏酰吡喃葡萄糖基)(1→6)-[β-D-吡喃葡萄糖基(1→2)]-β-D-吡喃葡萄糖苷,命名为唐古特苷A(1),以及12个已知化合物。通过核磁共振(NMR)和质谱(MS)实验对它们的结构进行了鉴定。此外,化合物1在体外能促进伴刀豆球蛋白A诱导的脾淋巴细胞和胸腺淋巴细胞增殖。

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