National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, MS 38677, United States.
Fitoterapia. 2012 Mar;83(2):281-5. doi: 10.1016/j.fitote.2011.11.004. Epub 2011 Nov 9.
The ethylacetate and n-butanol fractions of ethanolic extract of Platanus orientalis leaves led to the isolation of new acylated flavonol glycoside as 3',5,7-trihydroxy-4'-methoxyflavonol 3-[O-2-O-(2,4-Dihydroxy)-E-cinnamoyl-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl (1→2)]-β-D-glucopyranoside, along with seven known compounds. All the compounds were characterized by NMR including 2D NMR techniques. The isolates were evaluated for NF-κB, nitric oxide (NO), aromatase and QR2 chemoprevention activities and some of them appeared to be modestly active.
悬铃木叶乙醇提取物的乙酸乙酯和正丁醇部分导致了新的酰化黄酮醇糖苷的分离，即 3',5,7-三羟基-4'-甲氧基黄酮醇 3-[O-2-O-(2,4-二羟基)-E-肉桂酰基-α-L-鼠李吡喃糖基-(1→6)-β-D-吡喃葡萄糖基(1→2)]-β-D-吡喃葡萄糖苷，以及七种已知化合物。所有化合物均通过 NMR 包括 2D NMR 技术进行了表征。对这些分离物进行了 NF-κB、一氧化氮 (NO)、芳香酶和 QR2 化学预防活性的评估，其中一些表现出适度的活性。
