Talbot Ben Edward Michael, Webster Daniel, Fisher Martin, Alexander Eliza
Renal Unit, Brighton and Sussex University Hospital, Brighton, UK.
BMJ Case Rep. 2011 May 12;2011:bcr0420114057. doi: 10.1136/bcr.04.2011.4057.
The authors report on a case of Listeria rhomboencepahlitis in a previously undiagnosed HIV positive man. This case is of interest as the incidence of Listeria has increased dramatically in recent years and so may increase in the HIV-infected population. The organism is inherently resistant to cephalosporin antibiotics, empirically employed in the treatment of central nervous system infections and thus highlights the need to include amoxicillin in meningitis treatment regimes in patients at risk of HIV infection as well as the older and those known to be immuno-compromised.
作者报告了一例先前未确诊的HIV阳性男性患菱形脑炎李斯特菌病的病例。该病例之所以令人关注，是因为近年来李斯特菌的发病率急剧上升，在HIV感染人群中可能也会增加。该病原体对经验性用于治疗中枢神经系统感染的头孢菌素类抗生素具有固有抗性，因此凸显了在HIV感染风险患者以及老年人和已知免疫功能低下者的脑膜炎治疗方案中加入阿莫西林的必要性。
