Department of Pediatrics, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037, China.
BMC Pediatr. 2012 Jun 14;12:72. doi: 10.1186/1471-2431-12-72.
Chinese primary care settings have a heavy patient load, shortage of physicians, limited medical resources and low medical literacy, making it difficult to screen for developmental disorders in infants. The Infant Neurological International Battery (INFANIB) for the assessment of neuromotor developmental disorders in infants aged 0 ~ 18 months is widely applied in community health service centers because of its simplicity, time-saving advantages and short learning curve. We aimed to develop and assess a Chinese version of the INFANIB.
A Chinese version of the INFANIB was developed. Fifty-five preterm and 49 full-term infants with high risk of neurodevelopmental delays were assessed using the Chinese version of the INFANIB at 3, 7 and 10 months after birth. The Peabody Developmental Motor Scale (PDMS) was simultaneously used to assess the children with abnormalities and diagnose cerebral palsy. The sensitivity, specificity, positive predictive value and negative predictive value of the scale were calculated.
At birth, a higher proportion of full-term infants had asphyxia (p < 0.001), brain damage ( p = 0.003) and hyperbilirubinemia ( p = 0.022). The interclass correlation coefficient and intraclass correlation coefficient values for the INFANIB at 3, 7 and 10 months were >0.8, indicating excellent reliability with regard to inter- and intraobserver differences. The specificity, sensitivity, positive predictive value and negative predictive value were high for both high-risk premature infants and full-term infants at the age of 10 months. For premature infants at the age of 7 months or below, INFANIB had low validity for detecting abnormalities.
The Chinese version of the INFANIB can be useful for screening infants with high-risk for neuromotor abnormality in Chinese primary care settings.
中国基层医疗单位存在患者量大、医师短缺、医疗资源有限、医学文化素养低等问题，导致难以对婴儿发育障碍进行筛查。婴儿神经国际检查量表（INFANIB）因其简单、省时、学习曲线短，在社区卫生服务中心得到广泛应用，可用于评估 0~18 个月婴儿的神经运动发育障碍。本研究旨在研制并评价该量表的中文版。
研制 INFANIB 中文版。在婴儿出生后 3、7、10 个月，对 55 例早产儿和 49 例足月高危儿使用该量表进行评估，同时使用 Peabody 发育运动量表（PDMS）对异常患儿进行评估，以诊断脑瘫。计算该量表的灵敏度、特异度、阳性预测值和阴性预测值。
出生时，足月高危儿中窒息（ p<0.001）、脑损伤（ p=0.003）和高胆红素血症（ p=0.022）的比例更高。INFANIB 在 3、7、10 个月的组内相关系数和组间相关系数均>0.8，表明观察者内和观察者间差异具有良好的可靠性。10 个月时，高危早产儿和足月婴儿的特异性、灵敏度、阳性预测值和阴性预测值均较高。7 个月及以下早产儿的 INFANIB 对异常的检出效度较低。
INFANIB 中文版可用于中国基层医疗单位对神经运动异常高危婴儿进行筛查。
