47 岁男性，感染 HIV 并伴有偏瘫。
47 year-old man with HIV infection and hemiplegia.
出版信息
Brain Pathol. 2012 Jul;22(4):567-70. doi: 10.1111/j.1750-3639.2012.00605.x.
Abstract
CNS aspergillosis is often missed in the setting of advanced HIV infection, especially in the absence of presumed risk factors such as neutropenia or prior steroid treatment. We describe the postmortem evaluation of the brain of a patient with AIDS that developed progressive neurologic deterioration. Sequence brain MRIs, CSF analysis, and multiple presumed treatments failed to reveal the possible causes or improve his ongoing condition. His brain autopsy showed numerous abscesses with septated hyphae consistent with CNS angioinvasive aspergillosis.
摘要
中枢神经系统曲霉病在晚期 HIV 感染中常被漏诊，尤其是在没有中性粒细胞减少或既往类固醇治疗等假定危险因素的情况下。我们描述了一例 AIDS 患者的尸检大脑评估，该患者出现进行性神经功能恶化。序列脑部 MRI、CSF 分析和多种假定治疗未能揭示可能的病因或改善其持续病情。他的大脑尸检显示了许多带有分隔菌丝的脓肿，符合中枢神经系统血管侵袭性曲霉病。
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