Institute of Experimental Plant Biology and Biotechnology, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Plant Cell Environ. 2012 Oct;35(10):1756-68. doi: 10.1111/j.1365-3040.2012.02559.x. Epub 2012 Jul 6.
For optimal plant growth and development, cellular nitrogen (N) metabolism must be closely coordinated with other metabolic pathways, and mitochondria are thought to play a central role in this process. Recent studies using genetically modified plants have provided insight into the role of mitochondria in N metabolism. Mitochondrial metabolism is linked with N assimilation by amino acid, carbon (C) and redox metabolism. Mitochondria are not only an important source of C skeletons for N incorporation, they also produce other necessary metabolites and energy used in N remobilization processes. Nitric oxide of mitochondrial origin regulates respiration and influences primary N metabolism. Here, we discuss the changes in mitochondrial metabolism during ammonium or nitrate nutrition and under low N conditions. We also describe the involvement of mitochondria in the redistribution of N during senescence. The aim of this review was to demonstrate the role of mitochondria as an integration point of N cellular metabolism.
为了实现植物的最佳生长和发育，细胞氮（N）代谢必须与其他代谢途径密切协调，而线粒体被认为在这个过程中发挥着核心作用。最近使用遗传修饰植物的研究为我们深入了解线粒体在 N 代谢中的作用提供了线索。线粒体代谢与氨基酸、碳（C）和氧化还原代谢的 N 同化有关。线粒体不仅是 N 掺入所需 C 骨架的重要来源，还产生其他必需的代谢物和能量，用于 N 再动员过程。线粒体来源的一氧化氮调节呼吸作用，并影响初级 N 代谢。在这里，我们讨论了在线粒体代谢在铵或硝酸盐营养和低 N 条件下的变化。我们还描述了线粒体在衰老过程中 N 再分配中的作用。本综述的目的是展示线粒体作为细胞 N 代谢整合点的作用。
