Department of Health Care Organization and Policy, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA.
Am J Public Health. 2012 Aug;102(8):e68-73. doi: 10.2105/AJPH.2012.300790. Epub 2012 Jun 14.
We examined how changes in risk factors over time influence fetal, first day, and combined fetal-first day mortality and subsequent racial/ethnic disparities.
We selected deliveries to US resident non-Hispanic White and Black mothers from the linked live birth-infant death cohort and fetal deaths files (1995-1996; 2001-2002) and calculated changes over time of mortality rates, odds, and relative odds ratios (RORs) overall and among mothers with modifiable risk factors (smoking, diabetes, or hypertensive disorders).
Adjusted odds ratios (AORs) for fetal mortality overall (AOR=0.99; 95% confidence interval [CI]=0.96, 1.01) and among Blacks (AOR=0.98; 95% CI=0.93, 1.03) indicated no change over time. Among women with modifiable risk factors, the RORs indicated no change in disparities. The ROR was not significant for fetal mortality (ROR=0.96; 95% CI=0.83, 1.01) among smokers, but there was evidence of some decline. There was evidence of increase in RORs in fetal death among mothers with diabetes and hypertensive disorders, but differences were not significant.
Disparities in fetal, first day, and combined fetal-first day mortality have persisted and reflect discrepancies in care provision or other factors more challenging to measure.
我们研究了随着时间的推移,风险因素的变化如何影响胎儿、第 1 天和胎儿-第 1 天合并死亡率,并随后导致种族/民族差异。
我们从美国居民非西班牙裔白人和黑人母亲的活产-婴儿死亡队列和胎儿死亡档案中选择分娩(1995-1996 年;2001-2002 年),并计算死亡率、比值比(OR)和相对比值比(ROR)随时间的变化,以及可改变的风险因素(吸烟、糖尿病或高血压疾病)的母亲。
整体胎儿死亡率的调整比值比(AOR=0.99;95%置信区间[CI]=0.96,1.01)和黑人的 AOR(AOR=0.98;95%CI=0.93,1.03)表明随时间没有变化。在有可改变的风险因素的女性中,ROR 表明差异没有变化。对于吸烟的女性,胎儿死亡率的 ROR 没有统计学意义(ROR=0.96;95%CI=0.83,1.01),但有一些下降的迹象。在患有糖尿病和高血压疾病的母亲中,胎儿死亡的 ROR 有增加的迹象,但差异不显著。
胎儿、第 1 天和胎儿-第 1 天合并死亡率的差异仍然存在,反映了护理提供方面的差异或其他更难衡量的因素。