Department of Psychology, University of Toledo, Toledo, OH 43606-3390, USA.
Psychiatry Res. 2012 Oct 30;199(3):169-73. doi: 10.1016/j.psychres.2012.05.018. Epub 2012 Jun 12.
Little research has examined the underlying symptom structure of major depressive disorder (MDD) symptoms based on DSM-IV criteria. Our aim was to analyze the symptom structure of major depression, using the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 was administered to a sample of 2615 Army National Guard soldiers from Ohio. A one-factor model of depression and three separate two-factor models previously established in the literature were evaluated using confirmatory factor analysis. Results demonstrated greater support for the two-factor models of depression than for the one-factor model. The best fitting model was the two-factor model of somatic and non-somatic symptoms supported previously by Krause et al. (2010) and Richardson and Richards (2008). Implications for understanding the components and mechanisms of MDD are discussed.
基于 DSM-IV 标准，很少有研究检查过重度抑郁症 (MDD) 症状的潜在症状结构。我们的目的是使用患者健康问卷-9（PHQ-9）分析重度抑郁症的症状结构。PHQ-9 被用于俄亥俄州的 2615 名陆军国民警卫队士兵样本。使用验证性因子分析评估了抑郁的单因素模型和文献中先前建立的三个独立的双因素模型。结果表明，双因素模型比单因素模型更能支持抑郁。拟合最好的模型是 Krause 等人（2010 年）和 Richardson 和 Richards（2008 年）支持的躯体和非躯体症状的双因素模型。讨论了理解 MDD 成分和机制的意义。
