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声辐射力脉冲弹性成像(ARFI)与瞬时弹性成像(TE)在评估慢性乙型和丙型肝炎患者肝纤维化中的比较研究。

Comparative study concerning the value of acoustic radiation force impulse elastography (ARFI) in comparison with transient elastography (TE) for the assessment of liver fibrosis in patients with chronic hepatitis B and C.

机构信息

Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania.

出版信息

Ultrasound Med Biol. 2012 Aug;38(8):1310-6. doi: 10.1016/j.ultrasmedbio.2012.03.011. Epub 2012 Jun 12.

Abstract

Our aim was to compare liver stiffness (LS) measurements by means of acoustic radiation force impulse (ARFI) elastography and transient elastography (TE) in patients with chronic hepatitis B and C, according to the severity of fibrosis. We also compared the correlation strength of ARFI and TE measurements with liver fibrosis. We included 53 patients with hepatitis B and 107 with hepatitis C in which liver biopsy, ARFI and TE measurements were performed in the same session. The mean LS values measured with ARFI were similar in patients with chronic hepatitis B and C and depended on the stage of fibrosis. The correlation strength of LS measurements by ARFI and by TE with fibrosis was similar in chronic hepatitis B and C patients. In conclusion, for the same stage of fibrosis, the mean LS values by ARFI were similar in patients with chronic hepatitis B and C. ARFI had similar predictive value with TE in both chronic viral hepatitis.

摘要

我们的目的是比较慢性乙型和丙型肝炎患者的声辐射脉冲弹性成像(ARFI)和瞬时弹性成像(TE)的肝硬度(LS)测量结果,根据纤维化的严重程度进行比较。我们还比较了 ARFI 和 TE 测量值与肝纤维化的相关性强度。我们纳入了 53 例乙型肝炎和 107 例丙型肝炎患者,这些患者在同一次检查中进行了肝活检、ARFI 和 TE 测量。ARFI 测量的 LS 值在慢性乙型和丙型肝炎患者中相似,且取决于纤维化的分期。ARFI 和 TE 的 LS 测量值与纤维化的相关性在慢性乙型和丙型肝炎患者中相似。总之,对于相同的纤维化分期,慢性乙型和丙型肝炎患者的 ARFI 平均 LS 值相似。ARFI 在两种慢性病毒性肝炎中的预测价值与 TE 相似。

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