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声辐射力脉冲弹性成像(ARFI)与瞬时弹性成像(TE)在评估慢性乙型和丙型肝炎患者肝纤维化中的比较研究。

Comparative study concerning the value of acoustic radiation force impulse elastography (ARFI) in comparison with transient elastography (TE) for the assessment of liver fibrosis in patients with chronic hepatitis B and C.

机构信息

Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania.

出版信息

Ultrasound Med Biol. 2012 Aug;38(8):1310-6. doi: 10.1016/j.ultrasmedbio.2012.03.011. Epub 2012 Jun 12.

DOI:10.1016/j.ultrasmedbio.2012.03.011
PMID:22698510
Abstract

Our aim was to compare liver stiffness (LS) measurements by means of acoustic radiation force impulse (ARFI) elastography and transient elastography (TE) in patients with chronic hepatitis B and C, according to the severity of fibrosis. We also compared the correlation strength of ARFI and TE measurements with liver fibrosis. We included 53 patients with hepatitis B and 107 with hepatitis C in which liver biopsy, ARFI and TE measurements were performed in the same session. The mean LS values measured with ARFI were similar in patients with chronic hepatitis B and C and depended on the stage of fibrosis. The correlation strength of LS measurements by ARFI and by TE with fibrosis was similar in chronic hepatitis B and C patients. In conclusion, for the same stage of fibrosis, the mean LS values by ARFI were similar in patients with chronic hepatitis B and C. ARFI had similar predictive value with TE in both chronic viral hepatitis.

摘要

我们的目的是比较慢性乙型和丙型肝炎患者的声辐射脉冲弹性成像(ARFI)和瞬时弹性成像(TE)的肝硬度(LS)测量结果,根据纤维化的严重程度进行比较。我们还比较了 ARFI 和 TE 测量值与肝纤维化的相关性强度。我们纳入了 53 例乙型肝炎和 107 例丙型肝炎患者,这些患者在同一次检查中进行了肝活检、ARFI 和 TE 测量。ARFI 测量的 LS 值在慢性乙型和丙型肝炎患者中相似,且取决于纤维化的分期。ARFI 和 TE 的 LS 测量值与纤维化的相关性在慢性乙型和丙型肝炎患者中相似。总之,对于相同的纤维化分期,慢性乙型和丙型肝炎患者的 ARFI 平均 LS 值相似。ARFI 在两种慢性病毒性肝炎中的预测价值与 TE 相似。

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