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评估阿尔茨海默病中的语言理解能力:代币测验的应用。

Evaluating language comprehension in Alzheimer's disease: the use of the Token test.

作者信息

Paula Jonas Jardim de, Bertola Laiss, Nicolato Rodrigo, Moraes Edgar Nunes de, Malloy-Diniz Leandro Fernandes

机构信息

Faculdade de Filosofia e Ciências Humanas da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte MG, Brazil.

出版信息

Arq Neuropsiquiatr. 2012 Jun;70(6):435-40. doi: 10.1590/s0004-282x2012000600010.

Abstract

OBJECTIVE

To analyze the psychometric properties of the Token test (TT), a verbal comprehension test, and its applicability to the diagnosis of mild Alzheimer's disease (AD).

METHODS

One hundred and sixty participants (80 AD and 80 controls) performed the TT and a short battery of neuropsychological tests designed to evaluate general cognitive status, working memory and executive functions. Internal consistency, factor structure, correlation with other measures and group comparisons were evaluated.

RESULTS

The test evinced good internal consistency and a bi-factorial structure (related to comprehension and attention). Differences between AD and controls were significant, however the TT presented only moderate sensitivity and specificity for the AD diagnosis.

CONCLUSION

The TT showed evidence of good psychometric properties and adequacy for characterizing comprehension deficits in AD, but it was not an appropriate test for the AD detection and diagnosis.

摘要

目的

分析言语理解测试——代币测试(TT)的心理测量特性及其在轻度阿尔茨海默病(AD)诊断中的适用性。

方法

160名参与者(80名AD患者和80名对照者)进行了TT测试以及一组旨在评估总体认知状态、工作记忆和执行功能的简短神经心理学测试。评估了内部一致性、因子结构、与其他测量方法的相关性以及组间比较。

结果

该测试表现出良好的内部一致性和双因子结构(与理解和注意力相关)。AD患者与对照者之间存在显著差异,然而TT对AD诊断仅表现出中等的敏感性和特异性。

结论

TT显示出良好的心理测量特性,足以表征AD中的理解缺陷,但它并非AD检测和诊断的合适测试。

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