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[大鼠非致死性γ射线照射后长时间肺组织质膜的腺苷酸环化酶活性]

[Adenylate cyclase activity of the plasma membranes of lung tissue at lengthy periods following non-lethal gamma-irradiation of rats].

作者信息

Slozhenikina L V, Ruda V P, Ushakova T E, Kuzin A M

出版信息

Radiobiologiia. 1990 Nov-Dec;30(6):830-3.

PMID:2270287
Abstract

Basal and stimulated activity of adenylate cyclase (cyclizing ATP-pyrophosphate lyase, E.C. 4.6.1.1., AC) in plasma membranes of pulmonary tissue was being studied during a year after fractionated irradiation of rats (2 GyX3). Basal and hormone-stimulated activity of AC was shown to vary significantly from normal 6 and 12 months after irradiation. The exposed membranes responded differently to AC activation by isoproterenol and F-.

摘要

在对大鼠进行分次照射(2 Gy×3)后的一年时间里,对肺组织质膜中腺苷酸环化酶(环化ATP - 焦磷酸裂解酶,E.C. 4.6.1.1.,AC)的基础活性和刺激活性进行了研究。结果显示,照射后6个月和12个月时,AC的基础活性和激素刺激活性与正常情况相比有显著差异。暴露的质膜对异丙肾上腺素和F - 激活AC的反应不同。

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