University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
J Urol. 2012 Aug;188(2):648-52. doi: 10.1016/j.juro.2012.03.118. Epub 2012 Jun 15.
We developed a prototype magnetic tool for ureteroscopic extraction of magnetized stone particles. We compared its efficiency for retrieving magnetized calcium oxalate monohydrate stone particles with that of a conventional nitinol basket from the pelvi-collecting system of a bench top ureteroscopic simulator.
Iron oxide microparticles were successfully bound to 1 to 1.5, 1.5 to 2 and 2 to 2.5 mm human calcium oxalate monohydrate stones. Several coated fragments of each size were implanted in the collecting system of a bench top ureteroscopic simulator. Five-minute timed stone extraction trials were performed for each fragment size using a back loaded 8Fr magnetic tool mounted on a 0.038-inch guidewire or a conventional basket. The median number of fragments retrieved per timed trial was compared for the magnetic tool vs the basket using the Mann-Whitney U test.
For 1 to 1.5 mm fragments the median number retrieved within 5 minutes was significantly higher for the prototype magnetic tool than for the nitinol basket (9.5 vs 3.5, p = 0.03). For 1.5 to 2 mm fragments the magnetic tool was more efficient but the difference in the number of fragments retrieved was not statistically significant (9.5 vs 4.5, p = 0.19). For 2 to 2.5 mm fragments there was no difference between the instruments in the number retrieved (6 per group, p = 1.0).
The prototype magnetic tool improved the efficiency of retrieving stone particles rendered paramagnetic that were less than 2 mm but showed no advantage for larger fragments. This system has the potential to decrease the number of small retained fragments after ureteroscopic lithotripsy.
我们开发了一种用于输尿管镜取石的磁性工具原型,旨在比较其从台式输尿管镜模拟器肾盂收集系统中取出磁化草酸钙一水合物结石颗粒的效率与传统镍钛诺篮的效率。
成功地将氧化铁微粒结合到 1 至 1.5、1.5 至 2 和 2 至 2.5 毫米的人草酸钙一水合物结石上。每个尺寸的几个涂层碎片被植入台式输尿管镜模拟器的收集系统中。使用加载在后的 8Fr 磁性工具(安装在 0.038 英寸导丝上)或传统篮子,对每个碎片尺寸进行 5 分钟的定时取石试验。使用 Mann-Whitney U 检验比较磁性工具与篮子每定时试验中取出的碎片中位数数量。
对于 1 至 1.5 毫米的碎片,原型磁性工具在 5 分钟内取出的中位数数量明显高于镍钛诺篮(9.5 比 3.5,p = 0.03)。对于 1.5 至 2 毫米的碎片,磁性工具更有效,但取出的碎片数量差异无统计学意义(9.5 比 4.5,p = 0.19)。对于 2 至 2.5 毫米的碎片,两种仪器取出的碎片数量没有差异(每组 6 个,p = 1.0)。
原型磁性工具提高了取回小于 2 毫米的磁化结石颗粒的效率,但对较大碎片没有优势。该系统有可能减少输尿管镜碎石术后小的残留碎片数量。