Division of Cancer Prevention and Control, CDC, Atlanta, Georgia 30341, USA.
Am J Prev Med. 2012 Jul;43(1):97-118. doi: 10.1016/j.amepre.2012.04.009.
Screening reduces mortality from breast, cervical, and colorectal cancers. The Guide to Community Preventive Services previously conducted systematic reviews on the effectiveness of 11 interventions to increase screening for these cancers. This article presents results of updated systematic reviews for nine of these interventions.
Five databases were searched for studies published during January 2004-October 2008. Studies had to (1) be a primary investigation of one or more intervention category; (2) be conducted in a country with a high-income economy; (3) provide information on at least one cancer screening outcome of interest; and (4) include screening use prior to intervention implementation or a concurrent group unexposed to the intervention category of interest. Forty-five studies were included in the reviews.
Recommendations were added for one-on-one education to increase screening with fecal occult blood testing (FOBT) and group education to increase mammography screening. Strength of evidence for client reminder interventions to increase FOBT screening was upgraded from sufficient to strong. Previous findings and recommendations for reducing out-of-pocket costs (breast cancer screening); provider assessment and feedback (breast, cervical, and FOBT screening); one-on-one education and client reminders (breast and cervical cancer screening); and reducing structural barriers (breast cancer and FOBT screening) were reaffirmed or unchanged. Evidence remains insufficient to determine effectiveness for the remaining screening tests and intervention categories.
Findings indicate new and reaffirmed interventions effective in promoting recommended cancer screening, including colorectal cancer screening. Findings can be used in community and healthcare settings to promote recommended care. Important research gaps also are described.
筛查可降低乳腺癌、宫颈癌和结直肠癌的死亡率。社区预防服务指南之前对 11 项增加这些癌症筛查的干预措施的有效性进行了系统评价。本文介绍了其中 9 项干预措施的最新系统评价结果。
五个数据库被用来搜索 2004 年 1 月至 2008 年 10 月期间发表的研究。研究必须:(1) 是对一个或多个干预类别的初步调查;(2) 在高收入经济体的国家进行;(3) 提供至少一个感兴趣的癌症筛查结果的信息;(4) 包括在干预实施之前或同时不暴露于感兴趣的干预类别下的筛查使用情况。共有 45 项研究被纳入了审查。
推荐对增加粪便潜血检测(FOBT)筛查的一对一教育和增加乳房 X 线摄影筛查的群体教育进行干预。加强对客户提醒干预以增加 FOBT 筛查的证据从充分升级为强有力。之前关于降低自付费用(乳腺癌筛查)、提供者评估和反馈(乳腺癌、宫颈癌和 FOBT 筛查)、一对一教育和客户提醒(乳腺癌和宫颈癌筛查)以及减少结构性障碍(乳腺癌和 FOBT 筛查)的发现和建议得到了重申或保持不变。对于其余的筛查测试和干预类别,证据仍然不足,无法确定其有效性。
研究结果表明,新的和重申的干预措施可以有效地促进推荐的癌症筛查,包括结直肠癌筛查。这些发现可以在社区和医疗保健环境中使用,以促进推荐的护理。还描述了重要的研究差距。