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密歇根州罗恩·戴维斯无烟空气法案对非吸烟酒吧员工中可替宁、烟草特异性肺致癌物水平和自述呼吸道症状严重程度的影响。

The impact of Michigan's Dr Ron Davis smoke-free air law on levels of cotinine, tobacco-specific lung carcinogen and severity of self-reported respiratory symptoms among non-smoking bar employees.

机构信息

Michigan Department of Community Health, Tobacco Control Program, Lansing, Michigan 48913, USA.

出版信息

Tob Control. 2012 Nov;21(6):593-5. doi: 10.1136/tobaccocontrol-2011-050328. Epub 2012 Jun 15.

DOI:10.1136/tobaccocontrol-2011-050328
PMID:22705599
Abstract

OBJECTIVE

To determine the impact on bar employee's health and exposure to secondhand smoke (SHS) before and after the implementation of Michigan's Dr Ron Davis smoke-free air law that went into effect on 1 May 2010, prohibiting smoking in places of work, including bars.

METHODS

This study used a pre/postintervention experimental design. The setting was bars in 12 Michigan counties. Subjects were bar employees, recruited through flyers and individual discussions with local health department staff. Participants completed a screening questionnaire to determine eligibility. A total of 40 eligible employees completed a demographic survey, provided urine samples for analysis of cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and completed questionnaires on respiratory and general health status 6 weeks before and 6-10 weeks after the law went into effect. The main outcome measures were urine samples for total cotinine and total NNAL and data from a self-administered respiratory and general health status questionnaire collected during the pre-law and post-law study periods.

RESULTS

There was a significant decrease in the mean cotinine levels from 35.9 ng/ml to a non-quantifiable value (p<0.001), and there was a significant reduction in the mean NNAL level from 0.086 pmol/ml to 0.034 pmol/ml (p<0.001) 2 months after implementation of the law. There was also a significant improvement in all six self-reported respiratory symptoms (p<0.001) and general health status (p<0.001).

CONCLUSIONS

The reduction in the SHS biomarkers cotinine and NNAL and reported improvement in respiratory health demonstrates that the Michigan smoke-free workplace law is protecting bar employee health.

摘要

目的

确定在密歇根州罗恩·戴维斯无烟空气法案(该法案于 2010 年 5 月 1 日生效,禁止工作场所包括酒吧吸烟)实施前后,酒吧员工的健康状况和二手烟(SHS)暴露情况的影响。

方法

本研究采用了前后干预实验设计。研究地点是密歇根州 12 个县的酒吧。研究对象是通过传单和与当地卫生部门工作人员的个别讨论招募的酒吧员工。参与者完成了筛选问卷以确定资格。共有 40 名符合条件的员工完成了人口统计学调查,提供尿液样本进行可替宁和 4-(甲基亚硝氨基)-1-(3-吡啶基)-1-丁醇(NNAL)分析,并在该法律生效前 6 周和生效后 6-10 周期间完成了呼吸和一般健康状况问卷。主要观察指标是总可替宁和总 NNAL 的尿液样本,以及在法律生效前后研究期间通过自我管理的呼吸和一般健康状况问卷收集的数据。

结果

可替宁水平从 35.9ng/ml 显著下降至无法定量值(p<0.001),NNAL 水平从 0.086pmol/ml 显著下降至 0.034pmol/ml(p<0.001),实施法律后 2 个月。所有六项自我报告的呼吸症状(p<0.001)和一般健康状况(p<0.001)也显著改善。

结论

SHS 生物标志物可替宁和 NNAL 的减少以及报告的呼吸健康改善表明,密歇根州无烟工作场所法律正在保护酒吧员工的健康。

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