Camargos Einstein Francisco, Oliveira Larissa de Freitas, Boaventura Thaís de Deus Vieira
Geriatric Medical Centre, University Hospital, Brasilia University, Brazil.
BMJ Case Rep. 2011 Mar 3;2011:bcr0920103340. doi: 10.1136/bcr.09.2010.3340.
Axonal degeneration is the most common type of neuropathy induced by medication. The literature describes isolated cases in which polyneuropathy of the lower limb was observed during treatment with statins. The authors present a case of polyneuropathy associated with the use of a statin. An 82-year-old female patient presented with a complaint of weakness and discomfort in her lower limbs after 7 years of therapy with simvastatin. The results of an electromyographic study were compatible with polyneuropathy (sensorimotor axonal neuropathy--moderate to severe). One month after the therapy with simvastatin was discontinued, the symptoms were reduced.
轴索性变性是药物引起的最常见的神经病变类型。文献中描述了一些孤立病例，即在使用他汀类药物治疗期间观察到下肢多发性神经病。作者报告了一例与使用他汀类药物相关的多发性神经病病例。一名82岁女性患者在使用辛伐他汀治疗7年后，出现下肢无力和不适的症状。肌电图研究结果符合多发性神经病（感觉运动性轴索性神经病——中度至重度）。停用辛伐他汀治疗1个月后，症状有所减轻。
