Kararizou E, Davaki P, Karandreas N, Davou R, Vassilopoulos D
Section of Neuropathology, Neurological Clinic of University of Athens Eginition Hospital, Athens, Greece.
Int J Neurosci. 2006 May;116(5):629-38. doi: 10.1080/00207450600592180.
In elderly patients, peripheral neuropathies are common and may lead to disability. In order to investigate the relative incidence of different polyneuropathies in the elderly focusing on the contribution of nerve biopsy to their diagnosis, the authors studied 74 patients over 65 years of age with clinical, laboratory, electrophysiological, and sural nerve biopsy findings of different types of polyneuropathy. Vasculitic polyneuropathy seemed to be the most common cause of disabling neuropathy in the elderly, followed by paraneoplasia and diabetes. The possible diagnosis of idiopathic axonal neuropathy in the nine cases with neuropathy of unknown origin is discussed.
在老年患者中，周围神经病变很常见，可能导致残疾。为了研究老年人中不同多发性神经病变的相对发病率，并重点关注神经活检对其诊断的作用，作者对74例65岁以上患有不同类型多发性神经病变且有临床、实验室、电生理和腓肠神经活检结果的患者进行了研究。血管炎性多发性神经病变似乎是老年人致残性神经病变最常见的原因，其次是副肿瘤综合征和糖尿病。文中还讨论了9例病因不明的神经病变患者可能诊断为特发性轴索性神经病变的情况。
