László A, Sohár I, Falkay G, Kovács A, Halmos V, Szabó J
Department of Pediatrics, A. Szent-Györgyi University Medical School, Szeged, Hungary.
Acta Obstet Gynecol Scand. 1990;69(5):397-8. doi: 10.3109/00016349009013300.
Lysosomal cysteine proteinases (cathepsin H, B + L) and metalloproteinase (MMP7-ase) activities were measured from early gestational period (6-12 weeks) in frozen, non-cultivated chorionic villi. The mean activity of cathepsin H was 50.99 mU/mg protein, of cathepsin B + L, 71.16 mU/mg protein, and of MMP7-ase, 16.16 mU/mg protein. The MMP7-ase enzyme activities showed a correlation with gestational age. There was a significant correlation between the activities of cathepsin H and MMP7-ase.
在冷冻的、未培养的绒毛膜绒毛中,从妊娠早期(6 - 12周)开始测量溶酶体半胱氨酸蛋白酶(组织蛋白酶H、B + L)和金属蛋白酶(MMP7酶)的活性。组织蛋白酶H的平均活性为50.99 mU/mg蛋白质,组织蛋白酶B + L为71.16 mU/mg蛋白质,MMP7酶为16.16 mU/mg蛋白质。MMP7酶的活性与胎龄相关。组织蛋白酶H和MMP7酶的活性之间存在显著相关性。