Division of Cardiology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Korean J Intern Med. 2012 Jun;27(2):216-20. doi: 10.3904/kjim.2012.27.2.216. Epub 2012 May 31.
Acute myopericarditis is usually caused by viral infections, and the most common cause of viral myopericarditis is coxsackieviruses. Diagnosis of myopericarditis is made based on clinical manifestations of myocardial (such as myocardial dysfunction and elevated serum cardiac enzyme levels) and pericardial (such as inflammatory pericardial effusion) involvement. Although endomyocardial biopsy is the gold standard for the confirmation of viral infection, serologic tests can be helpful. Conservative management is the mainstay of treatment in acute myopericarditis. We report here a case of a 24-year-old man with acute myopericarditis who presented with transient effusive-constrictive pericarditis. Echocardiography showed transient pericardial effusion with constrictive physiology and global regional wall motion abnormalities of the left ventricle. The patient also had an elevated serum troponin I level. A computed tomogram of the chest showed pericardial and pleural effusion, which resolved after 2 weeks of supportive treatment. Serologic testing revealed coxsackievirus A4 and B3 coinfection. The patient received conservative medical treatment, including nonsteroidal anti-inflammatory drugs, and he recovered completely with no complications.
急性心肌炎通常由病毒感染引起,而病毒性心肌炎最常见的病因是柯萨奇病毒。心肌炎的诊断基于心肌(如心肌功能障碍和血清心肌酶水平升高)和心包(如炎症性心包积液)受累的临床表现。虽然心肌活检是病毒感染的确证的金标准,但血清学检查可能有帮助。急性心肌炎的主要治疗方法是保守治疗。我们在此报告一例 24 岁男性急性心肌炎患者,表现为一过性渗出性缩窄性心包炎。超声心动图显示短暂的心包积液伴有缩窄性生理学和左心室整体区域性壁运动异常。该患者的血清肌钙蛋白 I 水平也升高。胸部计算机断层扫描显示心包和胸腔积液,经 2 周支持治疗后积液吸收。血清学检测显示柯萨奇病毒 A4 和 B3 混合感染。该患者接受了包括非甾体抗炎药在内的保守治疗,完全康复,无并发症。