Massachusetts Institute of Technology, 77 Massachussetts Avenue, The David H. Koch Institute, Cambridge, MA 02139, USA.
Adv Healthc Mater. 2012 Mar;1(2):164-7. doi: 10.1002/adhm.201100052.
A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.
一种包含 3D 微通道网络的装置(使用牺牲熔融纺丝微纤维制造)夹在光刻图案微流道之间,与简单的两个微流道层堆叠相比,可将可溶性化合物输送到更大的体积。这种改进的输送能力由于小直径通道的曲折网络而导致流体阻力增加。