Kim Yon Seon
Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
J Korean Surg Soc. 2012 Jun;82(6):385-8. doi: 10.4174/jkss.2012.82.6.385. Epub 2012 May 29.
Parathyroid carcinoma is a rare disease in pediatric patients. We present a case of a 13-year-old girl who presented to the Thyroid Department for an asymptomatic palpable neck mass for 1 year. The high levels of calcium, ionized calcium, and parathyroid hormone level along with parathyroid scintigraphy studies suggested primary hyperparathyroidism. Parathyroid carcinoma was confirmed by biopsy and pathologic examination after resection. Six months postoperatively, persistent hypercalcemia and multiple lung metastases were found on computed tomography. Bilateral lung wedge resection was performed. En bloc resection for primary parathyroid carcinoma and aggressive resection of metastatic disease is the most effective treatment to control hypercalcemia.
甲状旁腺癌在儿科患者中是一种罕见疾病。我们报告一例13岁女孩的病例,她因颈部可触及无症状肿块1年就诊于甲状腺科。高钙血症、离子钙和甲状旁腺激素水平升高,以及甲状旁腺闪烁扫描检查提示原发性甲状旁腺功能亢进。经活检及切除术后病理检查确诊为甲状旁腺癌。术后6个月,计算机断层扫描发现持续性高钙血症和多发肺转移。遂行双侧肺楔形切除术。原发性甲状旁腺癌整块切除及转移性疾病的积极切除是控制高钙血症最有效的治疗方法。