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转移性甲状旁腺癌伴高钙血症,切除术后出现低钙血症:一例报告

Hypercalcemia in metastatic parathyroid carcinoma followed by hypocalcemia after resection: A case report.

作者信息

Ohashi Takuya, Kawago Mitsumasa, Hirai Yoshimitsu, Yata Yumi, Fusamoto Aya, Iguchi Hideto, Nakaya Takahito, Kiyoi Megumi, Miyasaka Miwako, Kawaji Mari, Furuta Yuki, Nishimura Yoshiharu

机构信息

Department of Thoracic and Cardiovascular Surgery Wakayama Medical University Wakayama Japan.

出版信息

Respirol Case Rep. 2023 Jul 4;11(8):e01185. doi: 10.1002/rcr2.1185. eCollection 2023 Aug.

Abstract

A 72-year-old man was diagnosed with hypercalcaemia 13 years ago. He was diagnosed with hyperparathyroidism associated with a parathyroid tumour and surgery was performed. Postoperatively, his serum calcium levels, which had once normalized, rose again. Medical treatment for hypercalcaemia failed to control the condition. A chest computed tomography showed multiple pulmonary nodules which were diagnosed as pulmonary metastases of parathyroid carcinoma. The tumour was considered to be the cause of the hypercalcaemia and volume reduction surgery was performed. Immediately after surgery, the patient presented with hypocalcaemia and required calcium correction with Calcium Gluconate Hydrate. Since then, the serum calcium level has stabilized and the patient has progressed without medical treatment. Parathyroid carcinoma is rare. This is a valuable case in which the serum calcium level was controlled by surgery. The patient also developed post-operative hypocalcaemia, which should be reported.

摘要

一名72岁男性13年前被诊断为高钙血症。他被诊断为与甲状旁腺肿瘤相关的甲状旁腺功能亢进,并接受了手术。术后,他曾恢复正常的血清钙水平再次升高。高钙血症的药物治疗未能控制病情。胸部计算机断层扫描显示多个肺结节,被诊断为甲状旁腺癌的肺转移。该肿瘤被认为是高钙血症的病因,于是进行了减容手术。手术后,患者立即出现低钙血症,需要用葡萄糖酸钙进行补钙。从那时起,血清钙水平稳定,患者未经药物治疗病情好转。甲状旁腺癌很罕见。这是一个通过手术控制血清钙水平的有价值病例。患者术后还出现了低钙血症,应予以报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05c8/10318418/d40d1fa74f1b/RCR2-11-e01185-g001.jpg

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