Burkhart J E, Stobbe T J
National Institute for Occupational Safety and Health, Division of Respiratory Disease Studies, Morgantown, WV 26505.
Am Ind Hyg Assoc J. 1990 Dec;51(12):640-5. doi: 10.1080/15298669091370284.
Veterinary clinics are typically small businesses without access to sophisticated occupational safety and health programs that may exist for larger firms or hospitals. Exposures to waste anesthetic gases have been linked to a myriad of adverse health-related conditions. Excessive exposures to anesthetic agents are possible because many of the clinics use portable gas delivery carts that are not designed to capture waste gases. While scavenging systems are available to remove waste anesthetic gases, the cost may be prohibitive for smaller clinics and the effectiveness of these systems has not been fully established in veterinary clinics. The National Institute for Occupational Safety and Health (NIOSH) recommends limiting exposures to nitrous oxide (N2O) to a time-weighted average (TWA) concentration of 25 ppm and halogenated agents to 2 ppm. The NIOSH TWA is based on the weight of the agent collected from a 45-L air sample by charcoal adsorption over a sampling period not to exceed 1 hr. The NIOSH criteria state that, in most situations, control of N2O to the TWA as defined will result in levels of approximately 0.5 ppm of the halogenated agent. At present, no Occupational Safety and Health Administration (OSHA) permissible exposure level (PEL) exists for exposure to anesthetic agents; nor do specific recommendations exist for veterinary scavenging systems. Waste anesthetic gas exposures were determined using a modified MIRAN 1A at five veterinary clinics operating within the Morgantown, West Virginia, vicinity. For unscavenged systems of methoxyflurane and halothane, 1-hr time-weighted average exposures ranged from 0.5 to 45.5 ppm and 0.2 to 105.4 ppm, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
兽医诊所通常是小型企业,无法获得大型公司或医院可能拥有的复杂职业安全与健康计划。接触废弃麻醉气体与众多健康相关的不良状况有关。由于许多诊所使用的便携式气体输送推车并非设计用于收集废气,因此存在过度接触麻醉剂的可能性。虽然有清除系统可用于去除废弃麻醉气体,但成本可能令小型诊所望而却步,且这些系统在兽医诊所中的有效性尚未完全确立。美国国家职业安全与健康研究所(NIOSH)建议将一氧化二氮(N2O)的接触时间加权平均(TWA)浓度限制在25 ppm,卤化剂限制在2 ppm。NIOSH的TWA是基于在不超过1小时的采样期内通过活性炭吸附从45升空气样本中收集的药剂重量。NIOSH标准指出,在大多数情况下,将N2O控制在规定的TWA水平将导致卤化剂水平约为0.5 ppm。目前,美国职业安全与健康管理局(OSHA)没有针对接触麻醉剂的允许接触水平(PEL);对于兽医清除系统也没有具体建议。在西弗吉尼亚州摩根敦附近运营的五家兽医诊所,使用改良的MIRAN 1A测定了废弃麻醉气体的接触情况。对于未配备清除系统的甲氧氟烷和氟烷,1小时时间加权平均接触量分别为0.5至45.5 ppm和0.2至105.4 ppm。(摘要截断于250字)