Rampon S, Missioux D, Sarre J
Sem Hop. 1979;55(19-20):1031-3.
Thirty one patients with osteoarthritis (29 hips, 16 knees) were submitted to a treatment with sulindac at a daily dose of 200 mg bid suppositories during four weeks. This trial showed that the treatment brought relief of pain in the majority of patients. Compared with others previously prescribed drugs, sulindac was more effective (72%). Sulindac suppositories were well tolerated; only three drop-out because side-effects (gastro intestinal tract: 2, skin 1) have been reported. Sulindac suppositories tolerance was reported as good.
31例骨关节炎患者(29例髋关节,16例膝关节)接受了舒林酸治疗,采用每日剂量200mg、每日两次的栓剂,持续四周。该试验表明,该治疗使大多数患者的疼痛得到缓解。与先前使用的其他药物相比,舒林酸更有效(72%)。舒林酸栓剂耐受性良好;仅报告了3例因副作用退出治疗的情况(胃肠道:2例,皮肤:1例)。据报告舒林酸栓剂耐受性良好。