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舒林酸治疗软组织风湿病(髋及肩部关节周围病)(作者译)

[Sulindac in the treatment of soft tissue rheumatism (periarthropathy of the hip and shoulder (author's transl)].

作者信息

Siegmeth W, Hartmann G, Sieberer W

出版信息

Wien Med Wochenschr. 1980 Jul 31;130(13-14):492-5.

PMID:7424040
Abstract

Sulindac (Clinoril) was tested in an open clinical-therapeutical study with regard to its analgesic effect and the improvement of function in 20 patients of both sexes suffering from periarthropathy of the hip or shoulder. The treatment lasted 4 weeks. The therapeutic effect was judged on the basis of the influence on the spontaneous pain and on the pain by pressure, on the functional improvement and on the daily habits of the patients. It was noted, that there was a lasting improvement due to the analgesic effect already in the first week of therapy and an improvement of function in the second week of therapy in the majority of the cases. Sulindac was well tolerated. Laboratory findings in the beginning and at the end of the four weeks treatment period revealed no toxic effects on organs, particularly on hematopoietic system.

摘要

舒林酸(奇诺力)在一项开放性临床治疗研究中,针对20例患有髋关节或肩关节周围关节病的男女患者,测试了其镇痛效果及功能改善情况。治疗持续4周。根据对自发痛、压痛、功能改善以及患者日常习惯的影响来判断治疗效果。结果发现,多数病例在治疗第一周因镇痛作用疼痛即有持续改善,第二周功能得到改善。舒林酸耐受性良好。四周治疗期开始和结束时的实验室检查结果显示,该药对器官无毒性作用,尤其是对造血系统无毒性作用。

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