Department of Dermatology, University Hospital Jena, Erfurter Straße 35, D-07743 Jena, Germany.
Contact Dermatitis. 2012 Oct;67(4):229-33. doi: 10.1111/j.1600-0536.2012.02119.x. Epub 2012 Jun 18.
Skin protection creams (PCs) are used in the occupational setting to prevent irritant hand dermatitis. However, so far, the actual amounts of PC applied and the resulting dose per area unit on hands at work have not been a matter of systematic investigation. The quantities used in experimental studies investigating the efficacy of PCs range between 4 and 25 mg/cm(2).
To develop a practical and accurate method to analyse the actual consumed quantities of PCs at workplaces in relation to hand surface area.
Thirty-one hospital nurses without hand eczema were provided with a sample PC in special monitoring tubes with Medication Event Monitoring Systems (MEMS TrackCaps(®); Aardex Ltd, Zug, Switzerland), and used the product over 5 working days as usual. The consumption was calculated by weighing of the tubes and analysis of the application frequency, and related to the individual calculated hand surface area.
The mean PC dose applied was 0.97 ± 0.6 mg/cm(2).
The amounts of PC applied by hospital nurses were significantly lower than the amounts that have been used in experimental studies. The method appears to be suitable for use in different in occupational settings. Further investigations are needed to gain realistic insights into consumers' attitudes regarding PCs.
皮肤保护乳膏(PCs)在职业环境中用于预防刺激性手部皮炎。然而,迄今为止,工作中实际涂抹的 PC 量以及每单位手部面积的剂量尚未进行系统调查。在研究 PCs 功效的实验研究中,使用的数量在 4 至 25 mg/cm(2) 之间。
开发一种实用且准确的方法来分析与手部表面积相关的工作场所实际消耗的 PCs 量。
31 名没有手部湿疹的医院护士使用特殊监测管中的样本 PC 进行监测,其中装有 Medication Event Monitoring Systems(MEMS TrackCaps(®);Aardex Ltd,Zug,Switzerland),并像往常一样在 5 个工作日内使用该产品。通过称重管和分析应用频率来计算消耗量,并与个体计算的手部表面积相关联。
平均应用的 PC 剂量为 0.97 ± 0.6 mg/cm(2)。
医院护士使用的 PC 量明显低于实验研究中使用的量。该方法似乎适用于不同的职业环境。需要进一步调查以深入了解消费者对 PCs 的态度。