Di Battista L, Stio F, Guarino S, Galani A, Maturo A, Dimko M, Mancini M, Gallo P
University of Rome, Italy.
G Chir. 2012 May;33(5):182-5.
We report a rare case of a 50 year old man with renal squamous cell carcinoma (SCC) who first came to our attention with renal colic and fever not responding to antibiotic or analgesic treatment. He had a long history of kidney stones, but had not undergone any imaging in the last 5 years. Physical examination revealed tenderness and a palpable mass in the right flank and lumbar region. A whole body CT scan was performed, revealing an 11 cm mass in the right kidney infiltrating the inferior vena cava. There were areas of calcification within the mass and multiple stones within the renal pelvis. The tumor was considered unsuitable for resection according to radiological and clinical criteria. The mass was biopsied percutaneously under CT guidance and histological examination revealed squamous cell carcinoma of the renal pelvis. The patient was treated with neoadjuvant chemotherapy and embolization of the renal artery. He died one month after diagnosis. To our knowledge this is the second reported case in the world of renal SCC infiltrating the inferior vena cava and with kidney stones.
我们报告了一例罕见的50岁男性肾鳞状细胞癌(SCC)病例,该患者最初因肾绞痛和发热前来就诊,对抗生素或镇痛治疗无反应。他有长期肾结石病史,但过去5年未进行任何影像学检查。体格检查发现右侧胁腹和腰部有压痛及可触及肿块。进行了全身CT扫描,显示右肾有一个11厘米的肿块,侵犯下腔静脉。肿块内有钙化区域,肾盂内有多个结石。根据放射学和临床标准,该肿瘤被认为不宜切除。在CT引导下经皮对肿块进行活检,组织学检查显示为肾盂鳞状细胞癌。患者接受了新辅助化疗和肾动脉栓塞治疗。诊断后一个月死亡。据我们所知,这是世界上第二例报告的肾SCC侵犯下腔静脉并伴有肾结石的病例。