Audebert A A, Zylberait D, Krulik M, Debray J
Sem Hop. 1979;55(19-20):993-7.
11 patients experienced 40 intrathecal injections of cytotoxic drugs during the treatment of acute leukemia. Tiapride was used as a preventive or curative therapy for headache. Results were found excellent or good in 70% of cases. Frequency and intensity of headache were reduced by half. Tiapride seems more effective in early headache than in cephalalgia occuring later.
11例急性白血病患者在治疗期间接受了40次鞘内注射细胞毒性药物。使用硫必利作为头痛的预防性或治疗性药物。70%的病例结果为优或良。头痛的频率和强度降低了一半。硫必利似乎对早期头痛比对后期出现的头痛更有效。