Le Bigot P
Sem Hop. 1982 Sep 16;58(33):1908-9.
The effects of tiapride were studied in 180 patients, including 165 with cephalalgia originating in various causes and 15 with other types of pain. 110 of the 165 patients with cephalalgia completed the study; results were good or excellent in 78 (71%), with no differences related the the cause of the headache. 13 of the 15 patients with other types of pain completed the study, with good or excellent results in 10. Tiapride was given in a daily dose of three tablets a day in outpatients, and two daily intramuscular injections in hospitalized patients. Tolerance was excellent in 109 of the 123 patients (88%). Recorded side-effects were drowsiness in 4 patients, asthenia in 3, ebrious manifestations in 3, amenorrhea-galactorrhea in 2 and constipation in 2.
对180例患者进行了硫必利疗效研究，其中165例为各种原因引起的头痛患者，15例为其他类型疼痛患者。165例头痛患者中有110例完成了研究；78例（71%）效果良好或极佳，与头痛原因无关。15例其他类型疼痛患者中有13例完成了研究，10例效果良好或极佳。门诊患者硫必利每日剂量为三片，住院患者每日注射两次。123例患者中有109例（88%）耐受性极佳。记录的副作用包括4例嗜睡、3例乏力、3例醉酒表现、2例闭经-溢乳和2例便秘。
