University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Emerg Infect Dis. 2012 Jul;18(7):1107-14. doi: 10.3201/eid1807.101638.
After an imported case of Marburg hemorrhagic fever was reported in 2008 in the Netherlands, control measures to prevent transmission were implemented. To evaluate consequences of these measures, we administered a structured questionnaire to 130 contacts classified as either having high-risk or low-risk exposure to body fluids of the case-patient; 77 (59.2%) of 130 contacts responded. A total of 67 (87.0%) of 77 respondents agreed that temperature monitoring and reporting was necessary, significantly more often among high-risk than low-risk contacts (p<0.001). Strict compliance with daily temperature monitoring decreased from 80.5% (62/77) during week 1 to 66.2% (51/77) during week 3. Contacts expressed concern about development of Marburg hemorrhagic fever (58.4%, 45/77) and infecting a family member (40.2%, 31/77). High-risk contacts had significantly higher scores on psychological impact scales (p<0.001) during and after the monitoring period. Public health authorities should specifically address consequences of control measures on the daily life of contacts.
2008 年在荷兰报告了一起马尔堡出血热输入病例后，实施了控制措施以防止传播。为了评估这些措施的后果，我们向 130 名接触者发放了一份结构调查问卷，这些接触者被归类为与病例患者的体液有高风险或低风险接触；130 名接触者中有 77 名（59.2%）做出了回应。共有 77 名答复者中的 67 名（87.0%）同意体温监测和报告是必要的，高风险接触者的这一比例明显高于低风险接触者（p<0.001）。严格遵守每日体温监测的比例从第 1 周的 80.5%（62/77）下降到第 3 周的 66.2%（51/77）。接触者对马尔堡出血热的发展表示担忧（58.4%，45/77）和感染家庭成员（40.2%，31/77）。高风险接触者在监测期间和之后的心理影响量表上的得分明显更高（p<0.001）。公共卫生当局应特别解决控制措施对接触者日常生活的影响。
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